Today's journal articles

A comprehensive analysis of adiponectin QTLs using SNP association, SNP cis-effects on peripheral blood gene expression and gene expression correlation identified novel metabolic syndrome (MetS) genes with potential role in carcinogenesis and systemic inflammation.

AGGF1 is a novel anti-inflammatory factor associated with TNF-α-induced endothelial activation.

Do you need further information on any of the agents being evaluated in the trial(s) below?  Let us know...

New Clinical Trials

MK-8237 (SCH900237) Biomarker Study in Participants With House Dust Mite (HDM) Induced Allergic Rhinitis or Rhinoconjunctivitis (8237-009)

Safety, Tolerability, and Clinical Activity of ASM-024 Administered to Patients With GOLD 2 or GOLD 3 Chronic Obstructive Pulmonary Disease (COPD)

Previous Journal Entries

A Novel Anti-human ICOSL Monoclonal Antibody that Enhances IgG Production of B Cells.

Serum Amyloid A Promotes Lung Neutrophilia by Increasing IL-17A Levels in the Mucosa and γδ T Cells.

Pin1-FADD Interactions Regulate Fas-Mediated Apoptosis in Activated Eosinophils.

CD30L/CD30 is critical for maintenance of IL-17A-producing γδ T cells bearing Vγ6 in mucosa-associated tissues in mice.

Sinomenine Decreases MyD88 Expression and Improves Inflammation-Induced Joint Damage Progression and Symptoms in Rat Adjuvant-Induced Arthritis.

Effect of a New Class of Compounds of the Group of Substituted 5r1, 6h2-1,3,4-Thiadiazine-2-Amines on the Inflammatory and Cytokine Response in Experimental Myocardial Infarction.

Regulation of Th1 Cells and Experimental Autoimmune Encephalomyelitis by Glycogen Synthase Kinase-3.

High throughput sequencing of IL23R reveals a low-frequency non-synonymous SNP that is associated with Ankylosing spondylitis in a Han Chinese population.

Etanercept suppresses arteritis in a murine model of kawasaki disease: a comparative study involving different biological agents.

The Novel Role of IL-7 Ligation to IL-7 Receptor in Myeloid Cells of Rheumatoid Arthritis and Collagen-Induced Arthritis.

Absence of radiographic progression of hip arthritis during infliximab treatment for ankylosing spondylitis.

New Application of 18F-Fluoride PET for the Detection of Bone Remodeling in Early-Stage Osteoarthritis of the Hip.

Signal relay by CCR2 and formylpeptide receptor - 2 (Fpr2) in the recruitment of monocyte - derived dendritic cells in allergic airway inflammation.

Safety of biologics approved for treating rheumatoid arthritis: analysis of spontaneous reports of adverse events.

Achievement of clinical remission in patients with juvenile idiopathic arthritis under a 2-10-year Etanercept exposure.

Dopamine Receptor D3 Expressed on CD4+ T Cells Favors Neurodegeneration of Dopaminergic Neurons during Parkinson's Disease.

Exogenous Interleukin-6 Facilitated the Contraction of the Colon in a Depression Rat Model.

Lidocaine inhibits staphylococcal enterotoxin-stimulated activation of peripheral blood mononuclear cells from patients with atopic dermatitis.

Anti-inflammatory Effect of Obestatin and Ghrelin in DSS-Induced Colitis in Rats.

Sphingosine - 1 - phosphate (S1P) receptor agonists mediate pro - fibrotic responses in normal human lung fibroblasts via S1P2 and S1P3 receptors and Smad - independent signaling.

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Previous News Items

ChemoCentryx Announces Phase I Data With CCX507, Company\'s New Generation Orally Administered CCR9 Inhibitor

Biogen Idec Submits Application to FDA for Approval of PLEGRIDY™ (Peginterferon Beta-1a) in Multiple Sclerosis

Promedior Presents Encouraging Results from Clinical Study of PRM-151 in Patients with Idiopathic Pulmonary Fibrosis

Phase III results: tiotropium* Respimat® effective in symptomatic asthma patients despite at least ICS/LABA independent of their age, allergic status, smoking status and bronchodilator response

PROTALEX REPORTS POSITIVE INTERIM REVIEW OF PHASE 1b TRIAL OF PRTX-100 IN RHEUMATOID ARTHRITIS BY INDEPENDENT DATA SAFETY MONITORING COMMITTEE

Prosonix Initiates Phase 2 Clinical Study with PSX1002 in Patients with Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Positive results from a phase Ia study with MIV-711 for the treatment of skeletal disorders

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