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Today's headline articles The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. 
Today's journal articles
Interleukin 18 induces angiogenesis in vitro and in vivo via Src and Jnk kinases.
Five-day course of budesonide inhalation suspension is as effective as oral prednisolone in the treatment of mild to severe acute asthma exacerbations in adults.
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Previous Journal Entries
Twenty-six-week efficacy and safety study of mometasone furoate/formoterol 200/10 micrograms combination treatment in patients with persistent asthma previously receiving medium-dose inhaled corticosteroids.
Design, synthesis, and evaluation of quinazoline T cell proliferation inhibitors.
Cannabinoid agonist WIN55,212 in vitro inhibits interleukin-6 (IL-6) and monocyte chemo-attractant protein-1 (MCP-1) release by rat pancreatic acini and in vivo induces dual effects on the course of acute pancreatitis.
Discovery of imidazo[1,2 - b]pyridazine derivatives as IKKbeta inhibitors. Part 1: Hit - to - lead study and structure - activity relationship.
Targeted deletion of the tachykinin 4 gene (TAC4-/-) influences the early stages of B lymphocyte development.
Anti-TNF therapy is associated with an increased risk of serious infections in patients with rheumatoid arthritis especially in the first 6 months of treatment: updated results from the British Society for Rheumatology Biologics Register with special emphasis on risks in the elderly.
Morphine sulfate and naltrexone hydrochloride extended release capsules in patients with chronic osteoarthritis pain.
Production and activation of matrix metalloproteinase 7 (matrilysin 1) in the lungs of patients with idiopathic pulmonary fibrosis.
Evaluation of the Architect((R)) tacrolimus assay in kidney, liver, and heart transplant recipients.
The nitric oxide-donating pravastatin, NCX 6550, inhibits cytokine release and NF-kappaB activation while enhancing PPARgamma expression in human monocyte/macrophages.
Preclinical and clinical investigation of a CCR5 antagonist, AZD5672, in patients with rheumatoid arthritis receiving methotrexate.
A novel tolerogenic peptide, hCDR1, for the specific treatment of systemic lupus erythematosus.
American College of Rheumatology 2010 recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis.
Gremlin is a novel agonist of the major pro-angiogenic receptor VEGFR2.
Tissue-derived proinflammatory effect of adenosine A(2B) receptor in lung ischemia-reperfusion injury.
Therapeutic potential of TGF-beta-induced CD4(+) Foxp3(+) regulatory T cells in autoimmune diseases.
Mechanisms of relaxant activity of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in rat tracheal smooth muscle.
Nicotinic acetylcholine receptor alpha1 promotes calpain-1 activation and macrophage inflammation in hypercholesterolemic nephropathy.
Combined Treatment With Formoterol and Tiotropium Is More Efficacious Than Treatment With Tiotropium Alone in Patients With Chronic Obstructive Pulmonary Disease, Regardless of Smoking Status, Inhaled Corticosteroid Use, Baseline Severity, or Gender.
Treatment with the Bcl-xL inhibitor ABT-737 in combination with interferon {alpha} specifically targets JAK2V617F positive polycythemia vera hematopoietic progenitor cells.
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Today's News Items
STX-100 granted orphan drug status for idiopathic pulmonary fibrosis
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