Today's journal articles

Immunogenicity and efficacy of two types of West Nile virus-like particles different in size and maturation as a second-generation vaccine candidate.

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New Clinical Trials

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Previous Journal Entries

Synthesis and evaluation of novel antifungal agents - quinoline and pyridine amide derivatives. Licensing Opportunity

Discovery of achiral inhibitors of the hepatitis C virus NS3 protease based on 2(1H) - pyrazinones.

ADS-J1 inhibits HIV-1 entry by interacting with gp120 and does not block the fusion-active gp41 core formation.

New 4H - chromen - 4 - one and 2H - chromene derivatives as anti - picornavirus capsid - binders.

Design, synthesis, and in vitro antiprotozoal, antimycobacterial activities of N - {2 - [(7 - chloroquinolin - 4 - yl)amino]ethyl}ureas.

Development of 2 - pyrrolidinyl - N - methyl pyrimidones as potent and orally bioavailable HIV integrase inhibitors.

Conjugates of betulin derivatives with AZT as potent anti - HIV agents.

Phase 2a Study of the CCR5 Monoclonal Antibody PRO 140 Administered Intravenously to HIV-infected Adults.

Peptide ligands selected with CD4-induced epitopes on native dualtropic HIV-1 envelope proteins mimic extracellular coreceptor domains and bind to HIV-1 gp120 independently of coreceptor usage.

Exploration of a new series of CCR5 antagonists: Multi - dimensional optimization of a sub - series containing N - substituted pyrazoles.

Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: A systematic review and meta-analysis.

Synthesis and bacterial biofilm inhibition studies of ethyl N - (2 - phenethyl) carbamate derivatives.

Challenges in the design and conduct of clinical trials for hospital-acquired pneumonia and ventilator-associated pneumonia: an industry perspective.

Adenosine receptor A3 is a critical mediator in LPS-induced pulmonary inflammation.

An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity.

Synthesis and anti - hepatitis C virus activity of novel ethyl 1H - indole - 3 - carboxylates in vitro.

4'' - O - (omega - Quinolylamino - alkylamino)propionyl derivatives of selected macrolides with the activity against the key erythromycin resistant respiratory pathogens.

Registration trials of antibacterial drugs for the treatment of nosocomial pneumonia.

Mortality, attributable mortality, and clinical events as end points for clinical trials of ventilator-associated pneumonia and hospital-acquired pneumonia.

Cost-effectiveness of human papillomavirus vaccination and screening in Spain.

Today's News Items

* * Inhibitex Successfully Completes Phase 1a Trial of INX-189

Approval to start Phase IIa clinical trial with Lytixar™ (LTX-109)

Abbott Receives FDA Approval for First Automated Molecular Test for Assessing Hepatitis B Treatment

Training Courses & Meetings

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Previous News Items

MedImmune receives complete response letter on motavizumab

Trius Therapeutics Initiates Phase 3 Program of Oral Torezolid Phosphate for the Treatment of ABSSSI

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