Bipolar Disorder - New treatments for bipolar depression set to drive near-term growth

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Publication Date: 2006-09-05

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Stimulated by sales of atypical antipsychotics for bipolar depression, and despite the launch of generic risperidone, the global bipolar disorder market will grow until 2011, when revenues will peak at $6.6 billion. The market will begin to decline thereafter owing to the launch of generic versions of the leading atypical antipsychotics, quetiapine, olanzapine, and ziprasidone from 2011 onwards.


Scope

  • Analysis of patient potential, unmet needs and clinical trial design in bipolar disorder
  • Overview of drugs in pre-registration, Phase III, II and I; with analysis of key companies involved in the market
  • Detailed profiles of key compounds in development for use in bipolar disorder, with forecasts of drug revenues to 2015
  • Discussion of indication expansion strategies and insight from key industry opinion leaders


    • Report Highlights
    AstraZeneca will be the first company to bring an atypical antipsychotic to the bipolar depression market as a monotherapy, following demonstration of efficacy with quetiapine. Pfizer will maintain a strong schizophrenia franchise by releasing asenapine to buffer the loss in revenue due to genericization of ziprasidone.

    Solvay/Wyeth/Lundbeck's bifeprunox will be the leading market entrant in terms of bipolar disorder specific sales revenue. These companies appear to be seeking initial license for bifeprunox in the bipolar depression indication, a tactic that will both increase the commercial viability of the drug and save time/money.

    Despite the commercial success of Lamictal (lamotrigine) and Depakote (valproate), the late-stage bipolar disorder pipeline only includes one anticonvulsant class molecule, Novartis' licarbazepine.


    Reasons to Purchase

  • Understand unmet needs in the bipolar disorder market based on key opinion leader comments
  • Benchmark key late-stage bipolar disorder compounds against current market leaders
  • Assess the global (US, Japan, five major EU) sales forecasts of late-stage pipeline drugs; and examine their clinical and commercial potential

    • Table of Contents

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