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- Effects of rapamycin on the arterial inflammatory response in atherosclerotic plaques in Apo-E knockout mice.
- Induction of T-cell immunity to antiretroviral drug-resistant human immunodeficiency virus type 1.
- Structural bioinformatics-based design of selective, irreversible kinase inhibitors.
- A prospective study of soluble tumor necrosis factor-alpha receptor II (sTNF-RII) and risk of coronary heart disease among women with type 2 diabetes.
- Parathyroid hormone-related protein overexpression decreases blood pressure in spontaneously hypertensive rats.
- Blockade of NF-kappaB ameliorates myocardial hypertrophy in response to chronic infusion of angiotensin II.
- Constitutively active HIF-1alpha improves perfusion and arterial remodeling in an endovascular model of limb ischemia.
- Effects of Atorvastatin on Th polarization in patients with acute myocardial infarction.
- Propranolol ameliorates and epinephrine exacerbates progression of acute and chronic viral myocarditis.
- Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI.
- The effect of tyrphostin AG-556 on intimal thickening in a mouse model of arterial injury.
- Gene transfer of a phospholamban-targeted antibody improves calcium handling and cardiac function in heart failure.
- Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities.
- Design, synthesis, and biological testing of thiosalicylamides as a novel class of calcium channel blockers.
- Design, synthesis, and structure-activity relationships of potent GPIIb/IIIa antagonists: discovery of FK419.
- Development of occlusive neointimal lesions in distal pulmonary arteries of endothelin B receptor-deficient rats: a new model of severe pulmonary arterial hypertension.
- Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats.
- Phenotypic knockout of VEGF-R2 and Tie-2 with an intradiabody reduces tumor growth and angiogenesis in vivo.
- Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells.
- Effects of antibiotic therapy on outcomes of patients with coronary artery disease: a meta-analysis of randomized controlled trials.
- Efficacy and safety of oral l-arginine in acute myocardial infarction. Results of the multicenter, randomized, double-blind, placebo-controlled ARAMI pilot trial.
- Vascular endothelial cell growth factor receptor 3-mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels.
- A novel peptide specifically binding to interleukin-6 receptor (gp80) inhibits angiogenesis and tumor growth.
- P53 mutation analysis of colorectal liver metastases: relation to actual survival, angiogenic status, and p53 overexpression.
- Combination therapy with interleukin-6 receptor superantagonist Sant7 and dexamethasone induces antitumor effects in a novel SCID-hu In vivo model of human multiple myeloma.
- Antiangiogenic treatment with endostatin inhibits progression of AML in vivo.
- Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
- Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure.
- Interleukin-4 can be a key positive regulator of inflammatory arthritis.
- Amelioration of rat adjuvant-induced arthritis by Met-RANTES.
- Angiotensin receptor blockers suppress antigen-specific T cell responses and ameliorate collagen-induced arthritis in mice.
- Metabolism investigation leading to novel drug design: orally active prostacyclin mimetics. Part 4.
- Discovery of new diphenyloxazole derivatives containing a pyrrolidine ring: orally active prostacyclin mimetics. Part 2.
- Aminoalkoxybenzyl pyrrolidines as novel human urotensin-II receptor antagonists.
- Water soluble prodrug of a COX-2 selective inhibitor suitable for intravenous administration in models of cerebral ischemia.
- Systemic bevacizumab (Avastin) therapy for neovascular age-related macular degeneration twelve-week results of an uncontrolled open-label clinical study.
- Doxorubicin induces cardiomyocyte dysfunction via a p38 MAP kinase-dependent oxidative stress mechanism.
- Neuroprotective effects of HSP70 overexpression after cerebral ischaemia--an MRI study.
- Fusogenic liposome delivers encapsulated nanoparticles for cytosolic controlled gene release.
- Postconditioning via stuttering reperfusion limits myocardial infarct size in rabbit hearts: role of ERK1/2.
- Thrombin inhibitors identified by computer-assisted multiparameter design.
- Cytoprotective effect of 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e) against ischemia/reperfusion-induced injury in rat heart involves inhibition of fodrin breakdown and protein tyrosine nitration.
- A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration.
- Angiotensin-converting enzyme inhibition and renal protection in nondiabetic patients: the data of the meta-analyses.
- The PPARdelta agonist GW0742X reduces atherosclerosis in LDLR(-/-) mice.
- Dysregulation of the endothelial nitric oxide synthase-soluble guanylate cyclase pathway is normalized by insulin in the aorta of diabetic rat.
- D-4F induces heme oxygenase-1 and extracellular superoxide dismutase, decreases endothelial cell sloughing, and improves vascular reactivity in rat model of diabetes.
- Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension.
- High-throughput screening of interactions between G protein-coupled receptors and ligands using confocal optics microscopy.
- The efficacy of sirolimus- and paclitaxel-eluting stents: a meta-analysis of randomized controlled trials.
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