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- A genetically engineered attenuated coxsackievirus B3 strain protects mice against lethal infection.
- Antithrombin ameliorates endotoxin-induced organ dysfunction more efficiently when combined with danaparoid sodium than with unfractionated heparin.
- Urokinase-type plasminogen activator, an endogenous antibiotic.
- Synthesis of 6-(3,5-dichlorobenzyl) derivatives as isosteric analogues of the HIV drug 6-(3,5-dimethylbenzyl)-1-(ethoxymethyl)-5-isopropyluracil (GCA-186).
- Identification of N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamides as a new class of HIV-1 entry inhibitors that prevent gp120 binding to CD4.
- Synthesis and biological evaluation of geminal disulfones as HIV-1 integrase inhibitors.
- Potent inhibitors of subgenomic hepatitis C virus RNA replication through optimization of indole-N-acetamide allosteric inhibitors of the viral NS5B polymerase.
- Synthesis and biological evaluation of acyclic 3-[(2-hydroxyethoxy)methyl] analogues of antiviral furo- and pyrrolo[2,3-d]pyrimidine nucleosides.
- Attenuated pathogenesis of polymicrobial peritonitis in mice after TLR2 agonist pre-treatment involves ST2 up-regulation.
- In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1.
- Angiotensin-converting enzyme 2 protects from severe acute lung failure.
- New alpha-methylene-gamma-butyrolactones with antimycobacterial properties.
- New HIV-1 replication inhibitors of the styryquinoline class bearing aroyl/acyl groups at the C-7 position: synthesis and biological activity.
- Synthesis and antiamoebic activity of new oxime ether derivatives containing 2-acetylpyridine/2-acetylfuran.
- Inhibition of hepatitis B virus gene expression and replication by helioxanthin and its derivative.
- Identification of heteroarylenamines as a new class of antituberculosis lead molecules.
- O-Methylglucogalloyl esters: synthesis and evaluation of their antimycotic activity.
- Isarfelin, a peptide with antifungal and insecticidal activities from Isaria felina.
- Angiopoietin-1 increases arteriolar vasoconstriction to phenylephrine during sepsis.
- HIV-1 Viral protein-r (Vpr) protects against lethal superantigen challenge while maintaining homeostatic T cell levels in vivo.
- A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury.
- HIF-1alpha expression regulates the bactericidal capacity of phagocytes.
- HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation.
- Effects of the terminal charges in human neutrophil alpha-defensin 2 on its bactericidal and membrane activity.
- Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas.
- Effect of ondansetron, a 5-HT3 receptor antagonist, on fatigue in chronic hepatitis C: a randomised, double blind, placebo controlled study.
- Early monitoring of ribavirin plasma concentrations may predict anemia and early virologic response in HIV/hepatitis C virus-coinfected patients.
- Curcumin has a palliative action on gentamicin-induced nephrotoxicity in rats.
- The beta2 integrin CD11c distinguishes a subset of cytotoxic pulmonary T cells with potent antiviral effects in vitro and in vivo.
- Protection mediated by antibodies to iron-regulated outer-membrane proteins of S. typhi in a mouse peritonitis model.
- An envelope-determined, pH-independent endocytic route of viral entry determines the susceptibility of human immunodeficiency virus type 1 (HIV-1) and HIV-2 to Lv2 restriction.
- Expression of interleukin-4 by recombinant respiratory syncytial virus is associated with accelerated inflammation and a nonfunctional cytotoxic T-lymphocyte response following primary infection but not following challenge with wild-type virus.
- CD4+ T-cell reconstitution reduces cytomegalovirus in the immunocompromised brain.
- Gene expression and antiviral activity of alpha/beta interferons and interleukin-29 in virus-infected human myeloid dendritic cells.
- The promiscuous CC chemokine receptor D6 is a functional coreceptor for primary isolates of human immunodeficiency virus type 1 (HIV-1) and HIV-2 on astrocytes.
- Evidence that low-level viremias during effective highly active antiretroviral therapy result from two processes: expression of archival virus and replication of virus.
- Hepatitis C virus stimulates the expression of cyclooxygenase-2 via oxidative stress: role of prostaglandin E2 in RNA replication.
- Deletion of the herpes simplex virus VP22-encoding gene (UL49) alters the expression, localization, and virion incorporation of ICP0.
- Human immunodeficiency virus reactivation by phorbol esters or T-cell receptor ligation requires both PKCalpha and PKCtheta.
- Age-dependent role for CCR5 in antiviral host defense against herpes simplex virus type 2.
- Genome-wide RNAi screen for host factors required for intracellular bacterial infection.
- Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection.
- The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease.
- The genome of the African trypanosome Trypanosoma brucei.
- The Trypanosoma cruzi proteome.
- Inhibition of Hepatitis B virus gene expression by single and dual small interfering RNA treatment.
- Comparative immunogenicity in rhesus monkeys of multi-protein HIV-1 (CRF02_AG) DNA/MVA vaccines expressing mature and immature VLPs.
- Performance of the Roche AMPLICOR human papillomavirus (HPV) test in prediction of cervical intraepithelial neoplasia (CIN) in women with abnormal PAP smear.
- High throughput screening assay for negative single stranded RNA virus polymerase inhibitors.
- The anti-HIV-1 effect of scutellarin.
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