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- Prime-boost vaccination with plasmid DNA and a chimeric adenovirus type 5 vector with type 35 fiber induces protective immunity against HIV.
- Prevention of recurrent lower urinary tract infections by long-term administration of fosfomycin trometamol. Double blind, randomized, parallel group, placebo controlled study.
- IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection.
- A soluble factor secreted by an HIV-1-resistant cell line blocks transcription through inactivating the DNA-binding capacity of the NF-kappa B p65/p50 dimer.
- Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity.
- Simultaneous detection of hepatitis C virus (HCV) core antigen and anti-HCV antibodies improves the early detection of HCV infection.
- Design of novel conformational and genotype-specific antigens for improving sensitivity of immunoassays for hepatitis C virus-specific antibodies.
- Evaluation of the ReSSQ assay in relation to the COBAS AMPLICOR CMV MONITOR test and an in-house nested PCR method for detection of cytomegalovirus DNA.
- Treatment of chronic hepatitis C virus infection via antioxidants: results of a phase I clinical trial.
- A phage-displayed cyclic peptide that interacts tightly with the immunodominant region of hepatitis B surface antigen.
- In vitro studies of cross-resistance mutations against two hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061.
- Evaluation of RIX4414, a live, attenuated rotavirus vaccine, in a randomized, double-blind, placebo-controlled phase 2 trial involving 2464 Singaporean infants.
- Lamivudine therapy in chronic delta hepatitis: a multicentre randomized-controlled pilot study.
- Domain 5 of high molecular weight kininogen is antibacterial.
- Major depressive episode with psychotic features induced by pegylated interferon-alpha-2b and ribavirin treatment.
- Acetylation of HIV-1 integrase by p300 regulates viral integration.
- Rifampicin+ceftriaxone versus vancomycin+ceftriaxone in the treatment of penicillin- and cephalosporin-resistant pneumococcal meningitis in an experimental rabbit model.
- Beta interferon and gamma interferon synergize to block viral DNA and virion synthesis in herpes simplex virus-infected cells.
- Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease.
- Bacterial toxins: potential weapons against HIV infection.
- Monoclonal antibody AP33 defines a broadly neutralizing epitope on the hepatitis C virus E2 envelope glycoprotein.
- The nonnucleoside reverse transcriptase inhibitor UC-781 inhibits human immunodeficiency virus type 1 infection of human cervical tissue and dissemination by migratory cells.
- Neuronal CXCL10 directs CD8+ T-cell recruitment and control of West Nile virus encephalitis.
- Replication of varicella-zoster virus in human skin organ culture.
- Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism. Part 1: eradication of Helicobacter in the cachexia of idiopathic parkinsonism.
- Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism. Part 2: response of facets of clinical idiopathic parkinsonism to Helicobacter pylori eradication. A randomized, double-blind, placebo-controlled efficacy study.
- Role of chronic infection and inflammation in the gastrointestinal tract in the etiology and pathogenesis of idiopathic parkinsonism. Part 3: predicted probability and gradients of severity of idiopathic parkinsonism based on H. pylori antibody profile.
- A molecular target for suppression of the evolution of antibiotic resistance: inhibition of the Escherichia coli RecA protein by N(6)-(1-naphthyl)-ADP.
- The protein farnesyltransferase inhibitor Tipifarnib as a new lead for the development of drugs against Chagas disease.
- Mapping antimalarial pharmacophores as a useful tool for the rapid discovery of drugs effective in vivo: design, construction, characterization, and pharmacology of metaquine.
- Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.
- Design and synthesis of a series of melamine-based nitroheterocycles with activity against Trypanosomatid parasites.
- Novel 8-substituted dipyridodiazepinone inhibitors with a broad-spectrum of activity against HIV-1 strains resistant to non-nucleoside reverse transcriptase inhibitors.
- RNA interference is an antiviral defence mechanism in Caenorhabditis elegans.
- Prevalence of drug-resistant HIV-1 variants in untreated individuals in Europe: implications for clinical management.
- Estimating HIV-1 drug resistance in antiretroviral-treated individuals in the United Kingdom.
- HIV-1 virologic and immunologic progression and initiation of antiretroviral therapy among HIV-1-infected subjects in a trial of the efficacy of recombinant glycoprotein 120 vaccine.
- Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock.
- Ability of orally administered IFN-alpha-containing transgenic potato extracts to inhibit Listeria monocytogenes infection.
- A novel HBV DNA vaccine based on T cell epitopes and its potential therapeutic effect in HBV transgenic mice.
- Novel sialic acid transporter of Haemophilus influenzae.
- Involvement of fractalkine/CX3CL1 expression by dendritic cells in the enhancement of host immunity against Legionella pneumophila.
- Involvement of toll-like receptor 2 in experimental invasive pulmonary aspergillosis.
- Characterization of MtsR, a new metal regulator in group A streptococcus, involved in iron acquisition and virulence.
- Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs.
- Cationic liposomes containing mycobacterial lipids: a new powerful Th1 adjuvant system.
- Toward a novel experimental model of infection to study American cutaneous leishmaniasis caused by Leishmania braziliensis.
- Isolation and partial purification of macrophage- and dendritic cell-activating components from Mycoplasma arthritidis: association with organism virulence and involvement with Toll-like receptor 2.
- Therapeutic efficacy of high-dose intravenous immunoglobulin in Mycobacterium tuberculosis infection in mice.
- CpG oligodeoxynucleotides increase the susceptibility of normal mice to infection by Candida albicans.
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