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- Efficacy of 2-(3,4-dimethyl-2,5-dihydro-1h-pyrrole-2-yl)-1-methylethyl pentanoate in a murine model of invasive aspergillosis.
- Clevudine inhibits hepatitis delta virus viremia: a pilot study of chronically infected woodchucks.
- In vitro activities of doripenem and comparator agents against 364 anaerobic clinical isolates.
- Dysregulation of bacterial proteolytic machinery by a new class of antibiotics.
- Cellular differentiation-induced attenuation of LPS response in HT-29 cells is related to the down-regulation of TLR4 expression.
- Modeling of activity of cyclic urea HIV-1 protease inhibitors using regularized-artificial neural networks.
- The bacterial HPr kinase/phosphorylase: a new type of Ser/Thr kinase as antimicrobial target.
- In silico fragment-based discovery of indolin-2-one analogues as potent DNA gyrase inhibitors.
- Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus.
- Anti-tubercular agents. Part 3. Benzothiadiazine as a novel scaffold for anti-Mycobacterium activity.
- Synthesis and biological evaluation of novel lipid A antagonists.
- Persistent NF-kappaB activation in renal epithelial cells in a mouse model of HIV-associated nephropathy.
- Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1.
- Molecular mechanisms of autoimmunity triggered by microbial infection.
- CCL5-CCR5 interaction provides antiapoptotic signals for macrophage survival during viral infection.
- Biochemical characterization of recombinant phosphoglucose isomerase of Mycobacterium tuberculosis.
- Synthesis of C-6 substituted pyrazolo[1,5-a]pyridines with potent activity against herpesviruses.
- Synthesis and in vitro anti-hepatitis B and C virus activities of ring-expanded ('fat') nucleobase analogues containing the imidazo[4,5-e][1,3]diazepine-4,8-dione ring system.
- Structure-activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors.
- A QSAR study on influenza neuraminidase inhibitors.
- Polymer-bound 6' sialyl-N-acetyllactosamine protects mice infected by influenza virus.
- 3D-QSAR study of ring-substituted quinoline class of anti-tuberculosis agents.
- The synthesis and biological evaluation of lactose-based sialylmimetics as inhibitors of rotaviral infection.
- Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: further evidence for survival and safety and implications for early treatment.
- Infusion of the beta-adrenergic blocker esmolol attenuates myocardial dysfunction in septic rats.
- Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus.
- Liver-directed gamma interferon gene delivery in chronic hepatitis C.
- Combinations of polyclonal or monoclonal antibodies to proteins of the outer membranes of the two infectious forms of vaccinia virus protect mice against a lethal respiratory challenge.
- Dynamic DNA methylation and histone modifications contribute to lentiviral transgene silencing in murine embryonic carcinoma cells.
- Comparative antigenicity and immunogenicity of hepadnavirus core proteins.
- Combinatorial approach to hepadnavirus-like particle vaccine design.
- Prophylactic alpha interferon treatment increases the therapeutic index of oncolytic vesicular stomatitis virus virotherapy for advanced hepatocellular carcinoma in immune-competent rats.
- LFA-1 is a key determinant for preferential infection of memory CD4+ T cells by human immunodeficiency virus type 1.
- An aptamer that neutralizes R5 strains of human immunodeficiency virus type 1 blocks gp120-CCR5 interaction.
- Synthesis and biological properties of 2-hydroxy-1-(1-phenyltetralyl)piperidine and some of its intermediates as derivatives of phencyclidine.
- Synthesis and evaluation of analgesic/ anti-inflammatory and antimicrobial activities of 3-substituted- 1,2,4-triazole-5-thiones.
- A dose-ranging study of the efficacy and tolerability of entecavir in Lamivudine-refractory chronic hepatitis B patients.
- Erythromycin ameliorates renal injury via anti-inflammatory effects in experimental diabetic rats.
- A randomized study of the use of fluconazole in continuous versus episodic therapy in patients with advanced HIV infection and a history of oropharyngeal candidiasis: AIDS Clinical Trials Group Study 323/Mycoses Study Group Study 40.
- Inhibition of human immunodeficiency virus-1 (HIV-1) by beta-chemokine analogues in mononuclear cells from HIV-1-infected patients with active tuberculosis.
- Prevalence and treatment of hepatitis C virus genotypes 4, 5, and 6.
- Solution structure of the human immunodeficiency virus type 1 p6 protein.
- p73 modulates HIV-1 Tat transcriptional and apoptotic activities in human astrocytes.
- Toll-like receptor 2 antagonists. Part 1: preliminary SAR investigation of novel synthetic phospholipids.
- Analogues of N-terminal truncated synthetic peptide fragments derived from RANTES inhibit HIV-1 infectivity.
- 3-Substituted indolizine-1-carbonitrile derivatives as phosphatase inhibitors.
- Identification and characterization of amino acid residues essential for the active site of UDP-N-acetylenolpyruvylglucosamine reductase (MurB) from Staphylococcus aureus.
- Negative regulation of Toll-like-receptor signaling by IRF-4.
- Single-dose azithromycin microspheres vs clarithromycin extended release for the treatment of mild-to-moderate community-acquired pneumonia in adults.
- Cutting edge: MyD88 controls phagocyte NADPH oxidase function and killing of gram-negative bacteria.
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