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- Phosphoramidate and phosphate prodrugs of (-)-beta-D-(2R,4R)-dioxolane-thymine: synthesis, anti-HIV activity and stability studies.
- The vaccine potential of Streptococcus pneumoniae surface lectin- and non-lectin proteins.
- Dengue tetravalent DNA vaccine inducing neutralizing antibody and anamnestic responses to four serotypes in mice.
- The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms.
- Vascular endothelial growth factor is increased during the first 48 hours of human septic shock and correlates with vascular permeability.
- The activity of pathway-selective estrogen receptor ligands in experimental septic shock.
- Macrophage migration inhibitory factor within the alveolar spaces induces changes in the heart during late experimental sepsis.
- Ability of the heparan sulfate proteoglycan syndecan-1 to participate in bacterial translocation across the intestinal epithelial barrier.
- Calcitonin gene-related peptide inhibits local acute inflammation and protects mice against lethal endotoxemia.
- Trends in health care resource use for hepatitis C virus infection in the United States.
- Adefovir rapidly suppresses hepatitis B in HBeAg-negative patients developing genotypic resistance to lamivudine.
- Synthesis and anti-HSV-1 activity of quinolonic acyclovir analogues.
- Safety and efficacy of influenza vaccination in systemic lupus erythematosus patients with quiescent disease.
- Effect of HIV-1 infection on antimalarial treatment outcomes in Uganda: a population-based study.
- PRO 2000 gel inhibits HIV and herpes simplex virus infection following vaginal application: a double-blind placebo-controlled trial.
- Enhancement of intranasal vaccination in mice with deglycosylated chain A ricin by LTR72, a novel mucosal adjuvant.
- From genome to drug lead: identification of a small-molecule inhibitor of the SARS virus.
- Integration site selection by HIV-based vectors in dividing and growth-arrested IMR-90 lung fibroblasts.
- Preclinical evaluation of cellular immune responses elicited by a polyvalent DNA prime/protein boost HIV-1 vaccine.
- Hepatitis C virus NS5B delays cell cycle progression by inducing interferon-beta via Toll-like receptor 3 signaling pathway without replicating viral genomes.
- Synthesis and in vitro anti-hepatitis B virus activities of some ethyl 5-hydroxy-1H-indole-3-carboxylates.
- HIV gp41-induced apoptosis is mediated by caspase-3-dependent mitochondrial depolarization, which is inhibited by HIV protease inhibitor nelfinavir.
- Oral delivery of lipid-encapsulated Mycobacterium bovis BCG extends survival of the bacillus in vivo and induces a long-term protective immune response against tuberculosis.
- Adverse events reported following live, cold-adapted, intranasal influenza vaccine.
- Comparison of two human immunodeficiency virus (HIV) RNA surrogate assays to the standard HIV RNA assay.
- The influence of G-CSF addition to antibiotic treatment of experimental sepsis on pulmonary tissue.
- Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand.
- Use of structure-based drug design approaches to obtain novel anthranilic acid acyl carrier protein synthase inhibitors.
- Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase.
- Antitrypanosomal, antileishmanial, and antimalarial activities of quaternary arylalkylammonium 2-amino-4-chlorophenyl phenyl sulfides, a new class of trypanothione reductase inhibitor, and of N-acyl derivatives of 2-amino-4-chlorophenyl phenyl sulfide.
- A new class of HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold.
- Expression profiling of herpesvirus and vaccinia virus proteins using a high-throughput baculovirus screening system.
- A role for heparan sulfate 3-O-sulfotransferase isoform 2 in herpes simplex virus type 1 entry and spread.
- Safety and immunogenicity of IMVAMUNE, a promising candidate as a third generation smallpox vaccine.
- Biological evaluation of isothiazoloquinolones containing aromatic heterocycles at the 7-position: In vitro activity of a series of potent antibacterial agents that are effective against methicillin-resistant Staphylococcus aureus.
- A molecule that is associated with Toll-like receptor 4 and regulates its cell surface expression.
- Randomised placebo controlled multicentre trial to assess short term clarithromycin for patients with stable coronary heart disease: CLARICOR trial.
- The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host.
- Herpesviral protein networks and their interaction with the human proteome.
- Disparate regulation and function of the class A scavenger receptors SR-AI/II and MARCO.
- Erythromycin differentially inhibits lipopolysaccharide- or poly(I:C)-induced but not peptidoglycan-induced activation of human monocyte-derived dendritic cells.
- E2 of hepatitis C virus inhibits apoptosis.
- Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders.
- An antiviral role for the RNA interference machinery in Caenorhabditis elegans.
- Neutralizing antibody responses drive the evolution of human immunodeficiency virus type 1 envelope during recent HIV infection.
- Synergistic in vitro interactions between (22S,23S)-3beta-bromo-5alpha,22,23-trihydroxystigmastan-6-one and acyclovir or foscarnet against herpes simplex virus type 1.
- Effects of the antifungal antibiotic clotrimazole on human cardiac repolarization potassium currents.
- The overproduction of nitric oxide associated with neutrophilic predominance is relevant to airway mycotic infections in asthmatics undergoing prolonged glucocorticoid treatment.
- The immunomodulator ginsan induces resistance to experimental sepsis by inhibiting Toll-like receptor-mediated inflammatory signals.
- RANTES, MDC and SDF-1alpha, prevent the HIVgp120-induced food and water intake decrease in rats.
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