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- Induction of a protein-targeted catalytic response in autoimmune prone mice: antibody-mediated cleavage of HIV-1 glycoprotein GP120.
- A pilot, open label, clinical trial using hydroxyzine in multiple sclerosis.
- The isolation and purification of biologically active recombinant and native autoantigens for the study of autoimmune disease.
- Immunogenicity and protection induced by Mycobacterium tuberculosis mce-2 and mce-3 mutants in a Balb/c mouse model of progressive pulmonary tuberculosis.
- Phase 1 randomized double-blind safety and immunogenicity trial of Plasmodium falciparum malaria merozoite surface protein FMP1 vaccine, adjuvanted with AS02A, in adults in western Kenya.
- Immunogenicity and protective efficacy in monkeys of purified inactivated Vero-cell SARS vaccine.
- Treatment of intractable painful diabetic neuropathy with intravenous lignocaine.
- Nucleoside and nucleotide inhibitors of HIV-1 replication.
- Vanilloid receptor (TRPV1)-deficient mice show increased susceptibility to dinitrobenzene sulfonic acid induced colitis.
- Elimination of innate immune responses and liver inflammation by PEGylation of adenoviral vectors and methylprednisolone.
- Characterisation of CD8 monoclonal antibody-induced protection from diabetes in NOD mice.
- Edaravone inhibits rheumatoid synovial cell proliferation and migration.
- TLR4-dependent hepcidin expression by myeloid cells in response to bacterial pathogens.
- Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level.
- Eptifibatide in peripheral vascular interventions: results of the Integrilin Reduces Inflammation in Peripheral Vascular Interventions (INFLAME) trial.
- Evaluating the role of the 620W allele of protein tyrosine phosphatase PTPN22 in Crohn's disease and multiple sclerosis.
- Protective effect of geranylgeranylacetone on trinitrobenzene sulfonic acid-induced colitis in mice.
- The free radical scavengers edaravone and tempol suppress experimental dextran sulfate sodium-induced colitis in mice.
- Blockade of interleukin 6 accelerates acinar cell apoptosis and attenuates experimental acute pancreatitis in vivo.
- DA-9201 shows anti-asthmatic effects by suppressing NF-kappaB expression in an ovalbumin-induced mouse model of asthma.
- Isothiazolopyridones: synthesis, structure, and biological activity of a new class of antibacterial agents.
- Synthesis and antiviral evaluation of cyclic and acyclic 2-methyl-3-hydroxy-4-pyridinone nucleoside derivatives.
- Matrix metalloproteinase target family landscape: a chemometrical approach to ligand selectivity based on protein binding site analysis.
- Discovery of nonpeptidic small-molecule AP-1 inhibitors: lead hopping based on a three-dimensional pharmacophore model.
- Structure-activity relationships of 2-chloro-N6-substituted-4'-thioadenosine-5'-uronamides as highly potent and selective agonists at the human A3 adenosine receptor.
- Design, synthesis, and structure-activity relationships of 1-,3-,8-, and 9-substituted-9-deazaxanthines at the human A2B adenosine receptor.
- Effects of oral bacterial immunotherapy in children with atopic eczema/dermatitis syndrome : a pilot study.
- Increased risk of intestinal cancer in Crohn's disease: a meta-analysis of population-based cohort studies.
- Risk of schizophrenia in people with coeliac disease, ulcerative colitis and Crohn's disease: a general population-based study.
- Effect of tranilast on matrix metalloproteinase production from neutrophils in-vitro.
- Tissue inhibitor of metalloproteinase 3 regulates TNF-dependent systemic inflammation.
- LF 15-0195 treatment protects against central nervous system autoimmunity by favoring the development of Foxp3-expressing regulatory CD4 T cells.
- Efficacy of human papillomavirus-16 vaccine to prevent cervical intraepithelial neoplasia: a randomized controlled trial.
- Therapeutic potential of oligonucleotides expressing immunosuppressive TTAGGG motifs.
- Iodinated N-acylvanillamines: potential "multiple-target" anti-inflammatory agents acting via the inhibition of t-cell activation and antagonism at vanilloid TRPV1 channels.
- Anti-inflammatory effect of propolis through inhibition of nitric oxide production on carrageenin-induced mouse paw edema.
- Non-methylated CpG motif packaged into fusogenic liposomes enhance antigen-specific immunity in mice.
- Comparisons of causes of death and mortality rates among HIV-infected persons: analysis of the pre-, early, and late HAART (highly active antiretroviral therapy) eras.
- Anti-infliximab antibodies in patients with rheumatoid arthritis who require higher doses of infliximab to achieve or maintain a clinical response.
- A multicenter, double-blind, randomized, placebo controlled trial of infliximab combined with low dose methotrexate in Japanese patients with rheumatoid arthritis.
- Safety of extended treatment with anakinra in patients with rheumatoid arthritis.
- Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial.
- Inhibition of MAP kinases by crude extract and pure compound isolated from Commiphora mukul leads to down regulation of TNF-alpha, IL-1beta and IL-2.
- The effect of triptolide on CD4+ and CD8+ cells in Peyer's patch of SD rats with collagen induced arthritis.
- Protective effects of antimicrobial peptides derived from the beetle Allomyrina dichotoma defensin on endotoxic shock in mice.
- Transient receptor potential vanilloid 1, calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis.
- Efficient nonviral gene delivery into primary lymphocytes from rats and mice.
- Possible role for mast cell-derived cathepsin G in the adverse remodelling of stenotic aortic valves.
- Therapeutic effect of urocortin and adrenomedullin in a murine model of Crohn's disease.
- MyD88 signaling controls autoimmune myocarditis induction.
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