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- The effect of hepatitis C on progression to AIDS before and after highly active antiretroviral therapy.
- Infection with concurrent multiple hepatitis C virus genotypes is associated with faster HIV disease progression.
- Animal models for studying respiratory syncytial virus infection and its long term effects on lung function.
- Survival in patients with HIV infection and viral hepatitis B or C: a cohort study.
- The HIV-1 nucleoside reverse transcriptase inhibitors stavudine and zidovudine alter adipocyte functions in vitro.
- The effects of HIV protease inhibitors atazanavir and lopinavir/ritonavir on insulin sensitivity in HIV-seronegative healthy adults.
- Acute renal failure in endotoxemia is dependent on caspase activation.
- Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3,3-diphenylpropyl)-piperidinyl amides and ureas.
- Anti-coxsackievirus B3 activity of 2-amino-3-nitropyrazolo[1,5-a]pyrimidines and their analogs.
- Design, synthesis and evaluation of 5-substituted amino-2,4-diamino-8-chloropyrimido-[4,5-b]quinolines as novel antimalarials.
- Optimization of pyrrolidinone based HIV protease inhibitors.
- Aminothiazole inhibitors of HCV RNA polymerase.
- Design, synthesis, and structural analysis of inhibitors of influenza neuraminidase containing a 2,3-disubstituted tetrahydrofuran-5-carboxylic acid core.
- Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.
- The selective cyclooxygenase-2 inhibitor nimesulide prevents Helicobacter pylori-associated gastric cancer development in a mouse model.
- IL-27 signaling compromises control of bacterial growth in mycobacteria-infected mice.
- A novel oral vehicle for poorly soluble HSV-helicase inhibitors: PK/PD validations.
- A systematic approach to the optimization of substrate-based inhibitors of the hepatitis C virus NS3 protease: discovery of potent and specific tripeptide inhibitors.
- Discovery of pyrano[3,4-b]indoles as potent and selective HCV NS5B polymerase inhibitors.
- Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database.
- Endothelin receptor antagonist bosentan improves survival in a murine caecal ligation and puncture model of septic shock.
- Effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on cardiovascular alterations in endotoxemia.
- Respiratory syncytial virus-induced exaggeration of allergic airway disease is dependent upon CCR1-associated immune responses.
- Synchronized infection of cell cultures by magnetically controlled virus.
- Drotrecogin alfa (activated) inhibits NF-kappa B activation and MIP-1-alpha release from isolated mononuclear cells of patients with severe sepsis.
- Activity, safety, and immunological effects of hydroxyurea added to didanosine in antiretroviral-naive and experienced HIV type 1-infected subjects: a randomized, placebo-controlled trial, ACTG 307.
- Orally active CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological activities of 1-benzazepine derivatives containing a sulfoxide moiety.
- CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological evaluation of piperidine-4-carboxamide derivatives.
- Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action?
- Pegylated interferon alfa-2b vs standard interferon alfa-2b, plus ribavirin, for chronic hepatitis C in HIV-infected patients: a randomized controlled trial.
- Risk of myocardial infarction and stroke after acute infection or vaccination.
- Modelling how ribavirin improves interferon response rates in hepatitis C virus infection.
- Pyrimidine containing RSV fusion inhibitors.
- Recombinant Listeria vaccines containing PEST sequences are potent immune adjuvants for the tumor-associated antigen human papillomavirus-16 E7.
- Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity.
- VFDB: a reference database for bacterial virulence factors.
- Protective role of angiopoietin-1 in endotoxic shock.
- PilX, a pilus-associated protein essential for bacterial aggregation, is a key to pilus-facilitated attachment of Neisseria meningitidis to human cells.
- Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins.
- Novel adeno-associated virus vector vaccine restricts replication of simian immunodeficiency virus in macaques.
- A novel class of inhibitors of peptide deformylase discovered through high-throughput screening and virtual ligand screening.
- Non-nucleoside benzimidazole-based allosteric inhibitors of the hepatitis C virus NS5B polymerase: inhibition of subgenomic hepatitis C virus RNA replicons in Huh-7 cells.
- Impairment of host resistance to Listeria monocytogenes infection in liver of db/db and ob/ob mice.
- In vitro and in vivo synergistic activities of linezolid combined with subinhibitory concentrations of imipenem against methicillin-resistant Staphylococcus aureus.
- Antifungal activities of R-135853, a sordarin derivative, in experimental candidiasis in mice.
- Identification of novel inhibitors of bacterial translation elongation factors.
- Pharmacokinetics, serum inhibitory and bactericidal activity, and safety of telavancin in healthy subjects.
- Single-dose safety and pharmacokinetics of amprenavir (141W94), a human immunodeficiency virus type 1 (HIV-1) protease inhibitor, in HIV-infected children.
- The novel parainfluenza virus hemagglutinin-neuraminidase inhibitor BCX 2798 prevents lethal synergism between a paramyxovirus and Streptococcus pneumoniae.
- Accurate multiplex gene synthesis from programmable DNA microchips.
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