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- A pneumococcal pilus influences virulence and host inflammatory responses.
- Administration of PUMA adenovirus increases the sensitivity of esophageal cancer cells to anticancer drugs.
- Low molecular weight indole fragments as IMPDH inhibitors.
- Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships.
- Fosamprenavir : clinical pharmacokinetics and drug interactions of the amprenavir prodrug.
- Pharmacokinetics of darbepoetin alfa after intravenous or subcutaneous administration in patients with non-myeloid malignancies undergoing chemotherapy.
- Intranasal IFNgamma extends passive IgA antibody protection of mice against Mycobacterium tuberculosis lung infection.
- Spirocyclopropyl pyrrolidines as a new series of alpha-L-fucosidase inhibitors.
- Downregulation by a long-acting beta2-adrenergic receptor agonist and corticosteroid of Staphylococcus aureus-induced airway epithelial inflammatory mediator production.
- Hypoactive sexual desire disorder in menopausal women: a survey of Western European women.
- Mycophenolate mofetil as first-line treatment improves clinically evident early scleroderma lung disease.
- Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates.
- Beneficial effects of switching from beta-blockers to nebivolol on the erectile function of hypertensive patients.
- Synthesis and smooth muscle-selective relaxant activity of a piperidine analogue: 1-(4'-fluorophenacyl)-4-hydroxy-4-phenyl-piperidinium chloride.
- Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia.
- TLR7/8 triggering exerts opposing effects in acute versus latent HIV infection.
- An antimicrobial cathelicidin peptide, human CAP18/LL-37, suppresses neutrophil apoptosis via the activation of formyl-peptide receptor-like 1 and P2X7.
- Vaccine-induced memory CD8+ T cells cannot prevent central nervous system virus reactivation.
- Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier.
- c-Jun kinase is a critical signaling molecule in a neonatal model of group B streptococcal sepsis.
- Synthesis, characterization and antiamoebic activity of 1-(thiazolo[4,5-b]quinoxaline-2-yl)-3-phenyl-2-pyrazoline derivatives.
- Anti-Plasmodium activity of imidazole-dioxolane compounds.
- Synthesis and antibacterial activities of chiral 1,3-oxazinan-2-one derivatives.
- In vitro activity of novel rifamycins against rifamycin-resistant Staphylococcus aureus.
- Telavancin versus standard therapy for treatment of complicated skin and skin structure infections caused by gram-positive bacteria: FAST 2 study.
- Preclinical profile of VX-950, a potent, selective, and orally bioavailable inhibitor of hepatitis C virus NS3-4A serine protease.
- Pharmacokinetic and safety evaluation of high-dose combinations of fosamprenavir and ritonavir.
- In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2',3'-dideoxy-3'-fluoroguanosine.
- SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of alpha interferon in replicon cells.
- Inactivation of herpes simplex virus clinical isolates by using a combination microbicide.
- In vitro development of resistance to human immunodeficiency virus protease inhibitor GW640385.
- Declining mortality in patients with acute renal failure, 1988 to 2002.
- Silencing of the laminin gamma-1 gene blocks Trypanosoma cruzi infection.
- Targeted delivery of ribavirin improves outcome of murine viral fulminant hepatitis via enhanced anti-viral activity.
- Efficient synthesis of novel NK1 receptor antagonists: selective 1,4-addition of grignard reagents to 6-chloronicotinic acid derivatives.
- Optimization of 2-aminothiazole derivatives as CCR4 antagonists.
- Anti-immunology: evasion of the host immune system by bacterial and viral pathogens.
- Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response.
- Low adherence to guidelines for preventing TB among persons with newly diagnosed HIV infection, United States.
- Impaired virus-induced interferon-alpha2 release in adult asthmatic patients.
- Probing of HIV-1 integrase/DNA interactions using novel analogs of viral DNA.
- The role of aminoglycosides in combination with a beta-lactam for the treatment of bacterial endocarditis: a meta-analysis of comparative trials.
- Intranasal vaccination with recombinant adeno-associated virus type 5 against human papillomavirus type 16 L1.
- Preclinical evaluation of two neutralizing human monoclonal antibodies against hepatitis C virus (HCV): a potential treatment to prevent HCV reinfection in liver transplant patients.
- Annexin 2: a novel human immunodeficiency virus type 1 Gag binding protein involved in replication in monocyte-derived macrophages.
- Innate immune responses to herpes simplex virus type 2 influence skin homing molecule expression by memory CD4+ lymphocytes.
- Reovirus delays diabetes onset but does not prevent insulitis in nonobese diabetic mice.
- The metabolism, pharmacokinetics and mechanisms of antiviral activity of ribavirin against hepatitis C virus.
- Acquired immunodeficiency syndrome-related lymphoma: simultaneous treatment with combined cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy and highly active antiretroviral therapy is safe and improves survival--results of the German Multicenter Trial.
- Tetrazole thioacetanilides: potent non-nucleoside inhibitors of WT HIV reverse transcriptase and its K103N mutant.
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