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- Human membrane protein Tim-3 facilitates hepatitis A virus entry into target cells.
- Design and synthesis of substrate and intermediate analogue inhibitors of S-ribosylhomocysteinase.
- A novel approach to the treatment of benign prostatic hyperplasia.
- Short- and long-term efficacy of solifenacin treatment in patients with symptoms of mixed urinary incontinence.
- Inhibition of HIV-1 replication by a peptide dimerization inhibitor of HIV-1 protease.
- Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4.
- Antibody to E1 peptide of hepatitis C virus genotype 4 inhibits virus binding and entry to HepG2 cells in vitro.
- Use of a novel assay based on intact recombinant viruses expressing green (EGFP) or red (DsRed2) fluorescent proteins to examine the contribution of pol and env genes to overall HIV-1 replicative fitness.
- Aggresomes and autophagy generate sites for virus replication.
- A single administration of lentiviral vectors expressing either full-length human immunodeficiency virus 1 (HIV-1)(HXB2) Rev/Env or codon-optimized HIV-1(JR-FL) gp120 generates durable immune responses in mice.
- NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner.
- A conditionally replicating HIV-based vector that stably expresses an antiviral shRNA against HIV-1 replication.
- Effect of doxazosin with and without rho-kinase inhibitor on human corpus cavernosum smooth muscle in the presence of bladder outlet obstruction.
- Propiverine compared to oxybutynin in neurogenic detrusor overactivity--results of a randomized, double-blind, multicenter clinical study.
- Long-term oral phosphodiesterase 5 inhibitor therapy alleviates recurrent priapism.
- Screening and evaluation of human single-chain fragment variable antibody against hepatitis B virus surface antigen.
- Evidence for potent autologous neutralizing antibody titers and compact envelopes in early infection with subtype C human immunodeficiency virus type 1.
- Mucosal administration of CpG oligodeoxynucleotide elicits strong CC and CXC chemokine responses in the vagina and serves as a potent Th1-tilting adjuvant for recombinant gD2 protein vaccination against genital herpes.
- Characterization of the early steps of hepatitis C virus infection by using luciferase reporter viruses.
- Recombinant adenoviral vectors can induce expression of p73 via the E4-orf6/7 protein.
- A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptors.
- Anti-V3 humanized antibody KD-247 effectively suppresses ex vivo generation of human immunodeficiency virus type 1 and affords sterile protection of monkeys against a heterologous simian/human immunodeficiency virus infection.
- Silencing of hepatitis A virus infection by small interfering RNAs.
- Measles virus V protein inhibits p53 family member p73.
- Characterization of GE82832, a peptide inhibitor of translocation interacting with bacterial 30S ribosomal subunits.
- Comparison of tazarotene and minocycline maintenance therapies in acne vulgaris: a multicenter, double-blind, randomized, parallel-group study.
- Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality.
- Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice.
- Structure-function engineering of interferon-beta-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation.
- Cost-effectiveness of West Nile virus vaccination.
- Participation of endogenous endothelin and ET(A) receptor in premicturition contractions in rats with bladder outlet obstruction.
- A high-throughput screening assay for the carboxyltransferase subunit of acetyl-CoA carboxylase.
- Evaluation of 10 commercial diagnostic kits for in vitro expressed hepatitis B virus (HBV) surface antigens encoded by HBV of genotypes A to H.
- The analytic sensitivity and mutant detection capability of six hepatitis B surface antigen assays.
- Improving anti-trypanosomal activity of 3-aminoquinoxaline-2-carbonitrile N1,N4-dioxide derivatives by complexation with vanadium.
- Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication.
- Platensimycin is a selective FabF inhibitor with potent antibiotic properties.
- Reprogramming of antiviral T cells prevents inactivation and restores T cell activity during persistent viral infection.
- Selection and characterization of an HIV-1 gp120-binding affibody ligand.
- Development of hepatitis B oral vaccine using B-cell epitope loaded PLG microparticles.
- Anti-HIV activity of stilbene-related heterocyclic compounds.
- Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase.
- Human recombinant antibodies against Plasmodium falciparum merozoite surface protein 3 cloned from peripheral blood leukocytes of individuals with immunity to malaria demonstrate antiparasitic properties.
- High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection.
- LL-37, the only human member of the cathelicidin family of antimicrobial peptides.
- Pharmacology of current and promising nucleosides for the treatment of human immunodeficiency viruses.
- Immune therapy including dendritic cell based therapy in chronic hepatitis B virus infection.
- Polycyclic peptide and glycopeptide antibiotics and their derivatives as inhibitors of HIV entry.
- Design, synthesis, and SAR studies of novel and highly active tri-cyclic HIV integrase inhibitors.
- Design, synthesis, and biological evaluation of novel tricyclic HIV-1 integrase inhibitors by modification of its pyridine ring.
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