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- Enhanced immunogenicity and protective efficacy with the use of interleukin-12-encapsulated microspheres plus AS01B in tuberculosis subunit vaccination.
- Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis.
- Novel bacterial acetyl coenzyme A carboxylase inhibitors with antibiotic efficacy in vivo.
- Fosmidomycin plus clindamycin for treatment of pediatric patients aged 1 to 14 years with Plasmodium falciparum malaria.
- Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia.
- AG205, a novel agent directed against FabK of Streptococcus pneumoniae.
- In vitro modeling of the HIV-macrophage reservoir.
- Synthesis and conformational analysis of His-Phe-Arg-Trp-NH2 and analogues with antifungal properties.
- Trends in herpes simplex virus type 1 and type 2 seroprevalence in the United States.
- Morphine withdrawal lowers host defense to enteric bacteria: spontaneous sepsis and increased sensitivity to oral Salmonella enterica serovar Typhimurium infection.
- Mechanisms of mortality in early and late sepsis.
- Comparative tolerability, safety and efficacy of tablet formulations of twice-daily clarithromycin 250 mg versus once-daily extended-release clarithromycin 500 mg in pediatric and adolescent patients.
- Long-term inhibition of hepatitis B virus in transgenic mice by double-stranded adeno-associated virus 8-delivered short hairpin RNA.
- Suppression of endotoxin-induced proinflammatory responses by citrus pectin through blocking LPS signaling pathways.
- Mechanisms of action of lysophospholipid analogues against trypanosomatid parasites.
- Determinants of activity of the HIV-1 maturation inhibitor PA-457.
- Virus-epitope vaccine design: informatic matching the HLA-I polymorphism to the virus genome.
- Inhibition of hepatitis B virus X gene expression by 10-23 DNAzymes.
- Antimalarial activity of N-alkyl amine, carboxamide, sulfonamide, and urea derivatives of a dispiro-1,2,4-trioxolane piperidine.
- Optimization of pyrimidinyl- and triazinyl-amines as non-nucleoside inhibitors of HIV-1 reverse transcriptase.
- Outcomes and treatment of acute hepatitis C virus infection in a United States population.
- Therapy insight: Use of melanocortin antagonists in the treatment of cachexia in chronic disease.
- Monoclonal antibody HCV-AbXTL68 in patients undergoing liver transplantation for HCV: results of a phase 2 randomized study.
- A new role for CCR5 in innate immunity--binding to bacterial heat shock protein 70.
- Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors.
- Structure, function and dynamics in the mur family of bacterial cell wall ligases.
- Immunogenicity of West Nile virus infectious DNA and its noninfectious derivatives.
- Regulation of CD4 expression via recycling by HRES-1/RAB4 controls susceptibility to HIV infection.
- The anti-hepatitis drug DDB chemosensitizes multidrug resistant cancer cells in vitro and in vivo by inhibiting P-gp and enhancing apoptosis.
- Cross-species hybridization of woodchuck hepatitis virus-induced hepatocellular carcinoma using human oligonucleotide microarrays.
- Gene expression analysis of primary normal human hepatocytes infected with human hepatitis B virus.
- Failure to implement evidence-based clinical guidelines for sepsis at the ED.
- A biosynthetic pathway for anandamide.
- Antibiotics modulate the stimulated cytokine response to endotoxin in a human ex vivo, in vitro model.
- In vitro cytotoxicity and mitochondrial toxicity of tenofovir alone and in combination with other antiretrovirals in human renal proximal tubule cells.
- Enhancement of antimicrobial activity against pseudomonas aeruginosa by coadministration of G10KHc and tobramycin.
- Population pharmacokinetics of atazanavir in patients with human immunodeficiency virus infection.
- Molecular mechanism of a thumb domain hepatitis C virus nonnucleoside RNA-dependent RNA polymerase inhibitor.
- Efficacy of novel rifamycin derivatives against rifamycin-sensitive and -resistant Staphylococcus aureus isolates in murine models of infection.
- Chain-terminating dinucleoside tetraphosphates are substrates for DNA polymerization by human immunodeficiency virus type 1 reverse transcriptase with increased activity against thymidine analogue-resistant mutants.
- Effect of treatment duration on pharmacokinetic/pharmacodynamic indices correlating with therapeutic efficacy of ceftazidime in experimental Klebsiella pneumoniae lung infection.
- NIM811, a cyclophilin inhibitor, exhibits potent in vitro activity against hepatitis C virus alone or in combination with alpha interferon.
- In silico identification and biological evaluation of antimicrobial peptides based on human cathelicidin LL-37.
- High-affinity aptamers to subtype 3a hepatitis C virus polymerase display genotypic specificity.
- Efficacy of cethromycin, a new ketolide, against Streptococcus pneumoniae susceptible or resistant to erythromycin in a murine pneumonia model.
- Critical design features of phenyl carboxylate-containing polymer microbicides.
- Computational prediction of the cross-reactive neutralizing epitope corresponding to the [corrected] monclonal [corrected] antibody b12 specific for HIV-1 gp120.
- Adeno-associated virus type 2 contains an integrin alpha5beta1 binding domain essential for viral cell entry.
- Role for 3-O-sulfated heparan sulfate as the receptor for herpes simplex virus type 1 entry into primary human corneal fibroblasts.
- Nelfinavir induces liposarcoma apoptosis and cell cycle arrest by upregulating sterol regulatory element binding protein-1.
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