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- Effect of a nitric oxide releasing derivative of paracetamol in a rat model of endotoxaemia.
- Inhibition of multidrug-resistant HIV-1 by interference with cellular S-adenosylmethionine decarboxylase activity.
- Gonococcal lipooligosaccharide suppresses HIV infection in human primary macrophages through induction of innate immunity.
- CD4+ immune escape and subsequent T-cell failure following chimpanzee immunization against hepatitis C virus.
- A chloroquine-like molecule designed to reverse resistance in Plasmodium falciparum.
- The alpha isoform of protein kinase CKI is responsible for hepatitis C virus NS5A hyperphosphorylation.
- Crystal structure of west nile virus envelope glycoprotein reveals viral surface epitopes.
- Inhibition of human immunodeficiency virus envelope glycoprotein- mediated single cell lysis by low-molecular-weight antagonists of viral entry.
- Design and mechanism of action of a novel bacteria-selective antimicrobial peptide from the cell-penetrating peptide Pep-1.
- Antiviral interactions of an HCV polymerase inhibitor with an HCV protease inhibitor or interferon in vitro.
- Discovery of potent inhibitors of pseudomonal quorum sensing via pharmacophore modeling and in silico screening.
- In vitro inhibitory activity of boropinic acid against Helicobacter pylori.
- Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA.
- Syntheses and studies of quinolone-cephalosporins as potential anti-tuberculosis agents.
- Non-nucleoside HIV-1 reverse transcriptase inhibitors, Part 7. Synthesis, antiviral activity, and 3D-QSAR investigations of novel 6-(1-naphthoyl) HEPT analogues.
- Naphtho[2,3-b][1,4]-thiazine-5,10-diones and 3-substituted-1,4-dioxo-1,4-dihydronaphthalen-2-yl-thioalkanoate derivatives: synthesis and biological evaluation as potential antibacterial and antifungal agents.
- Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1,2,3-triazole derivatives.
- Hydrazones of 2-aryl-quinoline-4-carboxylic acid hydrazides: synthesis and preliminary evaluation as antimicrobial agents.
- Parameters of inhibition of HIV-1 infection by small anionic microbicides.
- Antiviral effect of octyl gallate against DNA and RNA viruses.
- The cathepsin B inhibitor, z-FA-FMK, inhibits human T cell proliferation in vitro and modulates host response to pneumococcal infection in vivo.
- Evaluation of passively transferred, nonneutralizing antibody-dependent cellular cytotoxicity-mediating IgG in protection of neonatal rhesus macaques against oral SIVmac251 challenge.
- MaxiK blockade selectively inhibits the lipopolysaccharide-induced I kappa B-alpha /NF-kappa B signaling pathway in macrophages.
- Molecular and structural characterization of the domain 2 of hepatitis C virus non-structural protein 5A.
- Structure-activity relationship studies on the immune stimulatory effects of base-modified CpG toll-like receptor 9 agonists.
- A placebo-controlled study of memantine for the treatment of human immunodeficiency virus-associated sensory neuropathy.
- Peptide deformylase inhibitors as potent antimycobacterial agents.
- Peripheral neurotoxicity of pegylated interferon alpha: a prospective study in patients with HCV.
- Intranasal administration of adjuvant-combined recombinant influenza virus HA vaccine protects mice from the lethal H5N1 virus infection.
- The nucleotide-binding site of bacterial translation initiation factor 2 (IF2) as a metabolic sensor.
- Randomized, double-blind, placebo-controlled study of Malarone for malaria prophylaxis in non-immune Colombian soldiers.
- Structurally simple, potent, Plasmodium selective farnesyltransferase inhibitors that arrest the growth of malaria parasites.
- Accurate model predicting sustained response at week 4 of therapy with pegylated interferon with ribavirin in patients with chronic hepatitis C.
- Colistin as a salvage therapy for nosocomial infections caused by multidrug-resistant bacteria in the ICU.
- Synthesis of three classes of rhodacyanine dyes and evaluation of their in vitro and in vivo antimalarial activity.
- Cellular immune responses in children and adults receiving inactivated or live attenuated influenza vaccines.
- Oligomerization of hepatitis C virus core protein is crucial for interaction with the cytoplasmic domain of E1 envelope protein.
- Long-term protective immunity induced against Trypanosoma cruzi infection after vaccination with recombinant adenoviruses encoding amastigote surface protein-2 and trans-sialidase.
- N-trimethyl chitosan (TMC) nanoparticles loaded with influenza subunit antigen for intranasal vaccination: biological properties and immunogenicity in a mouse model.
- Selection on the human immunodeficiency virus type 1 proteome following primary infection.
- Human immunodeficiency virus type 1 V1-V2 envelope loop sequences expand and add glycosylation sites over the course of infection, and these modifications affect antibody neutralization sensitivity.
- An antiviral peptide inhibitor that is active against picornavirus 2A proteinases but not cellular caspases.
- Induction of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses in HIV vaccine trial participants who subsequently acquire HIV-1 infection.
- An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II.
- A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues.
- Etanercept reduces late endotoxin-induced pulmonary hypertension in the pig.
- Inhibition of HIV-1 replication by vesicular stomatitis virus envelope glycoprotein pseudotyped baculovirus vector-transduced ribozyme in mammalian cells.
- Safety and immunogenicity of an inactivated adjuvanted whole-virion influenza A (H5N1) vaccine: a phase I randomised controlled trial.
- Elafin prevents lipopolysaccharide-induced AP-1 and NF-kappaB activation via an effect on the ubiquitin-proteasome pathway.
- Protection against Pseudomonas aeruginosa pneumonia and sepsis-induced lung injury by overexpression of beta-defensin-2 in rats.
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