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- OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
- HIV protease inhibitors decrease VEGF/HIF-1alpha expression and angiogenesis in glioblastoma cells.
- HIV-1 infection and pathogenesis in a novel humanized mouse model.
- Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling.
- NFV, an HIV-1 protease inhibitor, induces growth arrest, reduced Akt signalling, apoptosis and docetaxel sensitisation in NSCLC cell lines.
- Entecavir resistance is rare in nucleoside naïve patients with hepatitis B.
- Surprises from the crystal structure of the hepatitis C virus NS2-3 protease.
- Synthesis and evaluation of isosteres of N-methyl indolo[3,2-b]-quinoline (cryptolepine) as new antiinfective agents.
- Design, synthesis, and in vivo evaluation of oxamniquine methacrylate and acrylamide prodrugs.
- A structural perspective on the interaction between lipopolysaccharide and factor C, a receptor involved in recognition of Gram-negative bacteria.
- Involvement of the PA28gamma-dependent pathway in insulin resistance induced by hepatitis C virus core protein.
- A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis.
- Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir.
- Prevalence of viral respiratory tract infections in children with asthma.
- Structure-antibacterial activity of arylcarbonyl- and arylsulfonyl-piperazine 5-triazolylmethyl oxazolidinones.
- Interaction of HCV core protein with 14-3-3epsilon protein releases Bax to activate apoptosis.
- euHCVdb: the European hepatitis C virus database.
- Human alpha- and beta-defensins block multiple steps in herpes simplex virus infection.
- Pseudomonas lipopolysaccharide accelerates wound repair via activation of a novel epithelial cell signaling cascade.
- Lysozyme-modified probiotic components protect rats against polymicrobial sepsis: role of macrophages and cathelicidin-related innate immunity.
- A randomized, double-blind, placebo-controlled trial of combined nevirapine and zidovudine compared with nevirapine alone in the prevention of perinatal transmission of HIV in Zimbabwe.
- Comparative biological and clinical outcomes after a switch from a virologically unsuccessful first protease inhibitor-containing antiretroviral combination to a 3-drug regimen containing efavirenz, nevirapine, or abacavir.
- Recommendations for the management of herpes zoster.
- Differences in viral kinetics between genotypes 1 and 3 of hepatitis C virus and between cirrhotic and non-cirrhotic patients during antiviral therapy.
- In vitro and in vivo activities of a new cephalosporin, FR264205, against Pseudomonas aeruginosa.
- APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection.
- Proteolytic processing of SDF-1alpha reveals a change in receptor specificity mediating HIV-associated neurodegeneration.
- Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands.
- High antiplasmodial activity of novel plasmepsins I and II inhibitors.
- Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases.
- Design, synthesis, and evaluation of efflux substrate-metal chelator conjugates as potential antimicrobial agents.
- The flexible and clustered lysine residues of human ribonuclease 7 are critical for membrane permeability and antimicrobial activity.
- In vitro antiviral activity of SCH446211 (SCH6), a novel inhibitor of the hepatitis C virus NS3 serine protease.
- Protective role of beta interferon in host defense against influenza A virus.
- Antiviral peptides targeting the west nile virus envelope protein.
- Klebsiella oxytoca as a causative organism of antibiotic-associated hemorrhagic colitis.
- The first experimental study on a candidate combined vaccine against hepatitis A and hepatitis E.
- Structure-activity relationship in the 3-iodo-4-phenoxypyridinone (IOPY) series: The nature of the C-3 substituent on anti-HIV activity.
- Parallel solid synthesis of inhibitors of the essential cell division FtsZ enzyme as a new potential class of antibacterials.
- Synthesis and biological evaluation of novel 5(H)-phenanthridin-6-ones, 5(H)-phenanthridin-6-one diketo acid, and polycyclic aromatic diketo acid analogs as new HIV-1 integrase inhibitors.
- Microarray-in-a-tube for detection of multiple viruses.
- Predicting the global spread of H5N1 avian influenza.
- Dual infection with HIV and malaria fuels the spread of both diseases in sub-Saharan Africa.
- An Alix fragment potently inhibits HIV-1 budding: characterization of binding to retroviral YPXL late domains.
- A comprehensive immunization strategy to eliminate transmission of hepatitis B virus infection in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP) Part II: immunization of adults.
- Generation and characterization of human monoclonal neutralizing antibodies with distinct binding and sequence features against SARS coronavirus using XenoMouse.
- Synthesis and antiviral properties of aza-analogues of acyclovir.
- Synthesis and biological activity of 5',9-anhydro-3-purine-isonucleosides as potential anti-hepatitis C virus agents.
- HIV-1 clones resistant to a small molecule CCR5 inhibitor use the inhibitor-bound form of CCR5 for entry.
- Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities.
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