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- Engineering the E. coli beta-galactosidase for the screening of antiviral protease inhibitors.
- A randomized, placebo-controlled study of the use of filgrastim in non neutropenic patients with nosocomial pneumonia.
- Antibody levels and protection after hepatitis B vaccination: results of a 15-year follow-up.
- Adefovir dipivoxil added to ongoing lamivudine therapy in patients with lamivudine-resistant hepatitis B e antigen-negative chronic hepatitis B.
- Development and preliminary optimization of indole-N-acetamide inhibitors of hepatitis C virus NS5B polymerase.
- Synthesis of phosphonated carbocyclic 2'-oxa-3'-aza-nucleosides: novel inhibitors of reverse transcriptase.
- Structure-based design, synthesis, and study of potent inhibitors of beta-ketoacyl-acyl carrier protein synthase III as potential antimicrobial agents.
- Identification of small molecule inhibitors of the hepatitis C virus RNA-dependent RNA polymerase from a pyrrolidine combinatorial mixture.
- Synthesis of isonicotinic acid N'-arylidene-N-[2-oxo-2-(4-aryl-piperazin-1-yl)-ethyl]-hydrazides as antituberculosis agents.
- Inhibitors of HCV NS5B polymerase: synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines.
- Design and synthesis of a potent macrocyclic 1,6-naphthyridine anti-human cytomegalovirus (HCMV) inhibitors.
- T-1249 retains potent antiretroviral activity in patients who had experienced virological failure while on an enfuvirtide-containing treatment regimen.
- The cellular HIV-1 Rev cofactor hRIP is required for viral replication.
- Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans.
- Lentiviral siRNAs targeting multiple highly conserved RNA sequences of human immunodeficiency virus type 1.
- PEGylated interferon alfa-2b and ribavirin treatment in patients with hepatitis C virus-related systemic vasculitis.
- Depression and clinical progression in HIV-infected drug users treated with highly active antiretroviral therapy.
- Viral interaction and responses in chronic hepatitis C and B coinfected patients with interferon-alpha plus ribavirin combination therapy.
- Response to interferon-based therapies in HIV-infected patients with chronic hepatitis C due to genotype 4.
- Phylloseptins: a novel class of anti-bacterial and anti-protozoan peptides from the Phyllomedusa genus.
- Novel TLR4-antagonizing peptides inhibit LPS-induced release of inflammatory mediators by monocytes.
- Protection against malaria induced by chirally modified Plasmodium falciparum's MSP-1 42 pseudopeptides.
- Engineering of vault nanocapsules with enzymatic and fluorescent properties.
- Synthesis of potent and selective inhibitors of Candida albicans N-myristoyltransferase based on the benzothiazole structure.
- Design, synthesis and evaluation of 2,4-diaminoquinazolines as inhibitors of trypanosomal and leishmanial dihydrofolate reductase.
- Synthesis and inhibitory activity of benzoic acid and pyridine derivatives on influenza neuraminidase.
- Attenuated fever response in mice lacking TRPV1.
- Potent inhibition of HIV-1 entry by (s4dU)35.
- The antimicrobial peptide dermaseptin S4 inhibits HIV-1 infectivity in vitro.
- 1,2,4-Triazino-[5,6b]indole derivatives: effects of the trifluoromethyl group on in vitro antimalarial activity.
- Effects of indomethacin on viral replication markers in asymptomatic carriers of hepatitis B: a randomized, placebo-controlled trial.
- Designer arrays for defined mutant analysis to detect genes essential for survival of Mycobacterium tuberculosis in mouse lungs.
- A1 adenosine receptor knockout mice exhibit increased mortality, renal dysfunction, and hepatic injury in murine septic peritonitis.
- Discovery and characterization of highly immunogenic and broadly recognized mimics of the HIV-1 CTL epitope Gag77-85.
- Prior elevation of IL-18 promotes rapid early IFN-gamma production during staphylococcal infection.
- Peptides derived from the reverse transcriptase of human immunodeficiency virus type 1 as novel inhibitors of the viral integrase.
- Recognition of bacterial glycosphingolipids by natural killer T cells.
- Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections.
- Etanercept as an adjuvant to interferon and ribavirin in treatment-naive patients with chronic hepatitis C virus infection: a phase 2 randomized, double-blind, placebo-controlled study.
- Antiviral activity of Cidofovir on a naturally human papillomavirus-16 infected squamous cell carcinoma of the head and neck (SCCHN) cell line improves radiation sensitivity.
- Activity of Hoechst 33258 against Pneumocystis carinii f. sp. muris, Candida albicans, and Candida dubliniensis.
- Comparative antimicrobial characterization of LBM415 (NVP PDF-713), a new peptide deformylase inhibitor of clinical importance.
- Comparative safety evaluation of the candidate vaginal microbicide C31G.
- Antifungal activity of flocculosin, a novel glycolipid isolated from Pseudozyma flocculosa.
- Mutant prevention concentrations of ABT-492, levofloxacin, moxifloxacin, and gatifloxacin against three common respiratory pathogens.
- SPL7013 gel as a topical microbicide for prevention of vaginal transmission of SHIV89.6P in macaques.
- Druggability indices for protein targets derived from NMR-based screening data.
- High-throughput lipophilicity measurement with immobilized artificial membranes.
- Lipopolysaccharide sequestrants: structural correlates of activity and toxicity in novel acylhomospermines.
- Synthesis of 2',3'-dideoxynucleoside 5'-alpha-P-borano-beta,gamma-(difluoromethylene)triphosphates and their inhibition of HIV-1 reverse transcriptase.
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