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- A novel peptide screened by phage display can mimic TRAP antigen epitope against Staphylococcus aureus infections.
- Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors.
- A randomized controlled trial to evaluate antiretroviral salvage therapy guided by rules-based or phenotype-driven HIV-1 genotypic drug-resistance interpretation with or without concentration-controlled intervention: the Resistance and Dosage Adapted Regimens (RADAR) study.
- 2H-Pyrrolo[3,4-b] [1,5]benzothiazepine derivatives as potential inhibitors of HIV-1 reverse transcriptase.
- Design, synthesis and biological evaluation of heteroaryl diketohexenoic and diketobutanoic acids as HIV-1 integrase inhibitors endowed with antiretroviral activity.
- Mesuol, a natural occurring 4-phenylcoumarin, inhibits HIV-1 replication by targeting the NF-kappaB pathway.
- Synthesis of glycoporphyrin derivatives and their antiviral activity against herpes simplex virus types 1 and 2.
- Linezolid for the treatment of multidrug-resistant tuberculosis.
- Continuous release of hepatitis C virus (HCV) by peripheral blood mononuclear cells and B-lymphoblastoid cell-line cultures derived from HCV-infected patients.
- Analysis of a 17-amino acid residue, virus-neutralizing microantibody.
- Protein farnesyltransferase inhibitors exhibit potent antimalarial activity.
- Synthesis, antiviral activity, and mechanism of drug resistance of D- and L-2',3'-didehydro-2',3'-dideoxy-2'-fluorocarbocyclic nucleosides.
- Synthesis and antibacterial properties of novel hydrolyzable cationic amphiphiles. Incorporation of multiple head groups leads to impressive antibacterial activity.
- Structure-based design, parallel synthesis, structure-activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse transcriptase inhibitor isosteres of phenethylthiazolylthiourea derivatives.
- Inhibition of herpes simplex virus thymidine kinases by 2-phenylamino-6-oxopurines and related compounds: structure-activity relationships and antiherpetic activity in vivo.
- Oxytocin protects against sepsis-induced multiple organ damage: role of neutrophils.
- Exploratory analysis for the evaluation of lopinavir/ritonavir-versus efavirenz-based HAART regimens in antiretroviral-naive HIV-positive patients: results from the Italian MASTER Cohort.
- In vitro antiviral activity and single-dose pharmacokinetics in humans of a novel, orally bioavailable inhibitor of human rhinovirus 3C protease.
- Bactericidal activity of the nitroimidazopyran PA-824 in a murine model of tuberculosis.
- Preclinical testing of the nitroimidazopyran PA-824 for activity against Mycobacterium tuberculosis in a series of in vitro and in vivo models.
- Combination of antimicrobial and endotoxin-neutralizing activities of novel oleoylamines.
- TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates.
- Small molecules VP-14637 and JNJ-2408068 inhibit respiratory syncytial virus fusion by similar mechanisms.
- In vitro and in vivo activities of DA-7867, a new oxazolidinone, against aerobic gram-positive bacteria.
- In vitro activity of doripenem (S-4661) against multidrug-resistant gram-negative bacilli isolated from patients with cystic fibrosis.
- Comparative in vitro activities of investigational peptide deformylase inhibitor NVP LBM-415 and other agents against human mycoplasmas and ureaplasmas.
- The synthetic peptide derived from the NH2-terminal extracellular region of an orphan G protein-coupled receptor, GPR1, preferentially inhibits infection of X4 HIV-1.
- Suppression of virus load by highly active antiretroviral therapy in rhesus macaques infected with a recombinant simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1.
- A virus-encoded inhibitor that blocks RNA interference in mammalian cells.
- A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins.
- Induction of T-cell immunity to antiretroviral drug-resistant human immunodeficiency virus type 1.
- G-protein signaling triggered by R5 human immunodeficiency virus type 1 increases virus replication efficiency in primary T lymphocytes.
- Structural bioinformatics-based design of selective, irreversible kinase inhibitors.
- Cloning, expression, and purification of HIV-2 gp125: A target for HIV vaccination.
- Propranolol ameliorates and epinephrine exacerbates progression of acute and chronic viral myocarditis.
- EBP2 plays a key role in Epstein-Barr virus mitotic segregation and is regulated by aurora family kinases.
- A new approach to an influenza live vaccine: modification of the cleavage site of hemagglutinin.
- Synthesis of substituted indole derivatives as a new class of antimalarial agents.
- Therapeutic immunization with a human immunodeficiency virus (HIV) type 1-recombinant canarypox vaccine in chronically HIV-infected patients: The Vacciter Study (ANRS 094).
- Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages.
- A monoclonal antibody that inhibits mycobacterial DNA gyrase by a novel mechanism.
- A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults.
- Hydroxymethylglutaryl co-enzyme A reductase inhibition attenuates endotoxin-mediated inflammatory responses.
- Hypersensitivity of HIV-1-infected cells to reactive sulfonamide metabolites correlated to expression of the HIV-1 viral protein tat.
- Fusogenic liposome delivers encapsulated nanoparticles for cytosolic controlled gene release.
- Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor.
- The human cathelicidin LL-37: a multifunctional peptide involved in infection and inflammation in the lung.
- High-throughput screening of interactions between G protein-coupled receptors and ligands using confocal optics microscopy.
- Anti-HIV activity of (-)-(2R,4R)-1- (2-hydroxymethyl-1,3-dioxolan-4-yl)-thymine against drug-resistant HIV-1 mutants and studies of its molecular mechanism.
- Structure-based characterization and optimization of novel hydrophobic binding interactions in a series of pyrrolidine influenza neuraminidase inhibitors.
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