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- The involvement of V(alpha)14 natural killer T cells in the pathogenesis of arthritis in murine models.
- Amelioration of rat adjuvant-induced arthritis by Met-RANTES.
- Angiotensin receptor blockers suppress antigen-specific T cell responses and ameliorate collagen-induced arthritis in mice.
- Metabolism investigation leading to novel drug design: orally active prostacyclin mimetics. Part 4.
- Discovery of new diphenyloxazole derivatives containing a pyrrolidine ring: orally active prostacyclin mimetics. Part 2.
- Treatment with oral bromelain decreases colonic inflammation in the IL-10-deficient murine model of inflammatory bowel disease.
- Fusogenic liposome delivers encapsulated nanoparticles for cytosolic controlled gene release.
- First study of infliximab treatment in patients with chronic obstructive pulmonary disease.
- NF-(kappa)B-inducing kinase controls lymphocyte and osteoclast activities in inflammatory arthritis.
- The human cathelicidin LL-37: a multifunctional peptide involved in infection and inflammation in the lung.
- Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation.
- High-throughput screening of interactions between G protein-coupled receptors and ligands using confocal optics microscopy.
- FTY720, a novel immunomodulator: efficacy and safety results from the first phase 2A study in de novo renal transplantation.
- Expression of the anaphylatoxin receptors C3aR and C5aR is increased in fatal asthma.
- Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation.
- Mycophenolate mofetil in systemic lupus erythematosus: efficacy and tolerability in 86 patients.
- Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis.
- Topical inhibition of nuclear factor-kappaB enhances reduction in lung edema by surfactant in a piglet model of airway lavage.
- Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
- Preparation and characterization of a monoclonal antibody against mannoprotein of Candida albicans.
- The non-MHC quantitative trait locus Cia5 contains three major arthritis genes that differentially regulate disease severity, pannus formation, and joint damage in collagen- and pristane-induced arthritis.
- Serum amyloid A-luciferase transgenic mice: response to sepsis, acute arthritis, and contact hypersensitivity and the effects of proteasome inhibition.
- The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease.
- Stem cell division is regulated by the microRNA pathway.
- Regression of mouse tumours and inhibition of metastases following administration of a Semliki Forest virus vector with enhanced expression of IL-12.
- Imiquimod and S-27609 as adjuvants of DNA vaccination in a transgenic murine model of HER2/neu-positive mammary carcinoma.
- 5-Lipoxygenase inhibitors attenuate growth of human renal cell carcinoma and induce apoptosis through arachidonic acid pathway.
- Th1-orientated immunological properties of the bacterial extract OM-85-BV.
- Progressive multifocal leukoencephalopathy in a patient treated with natalizumab.
- Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis.
- Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease.
- High-mobility group box 1 protein is an inflammatory mediator in necrotizing enterocolitis: protective effect of the macrophage deactivator semapimod.
- Type 2 diabetic mice have increased arteriolar tone and blood pressure: enhanced release of COX-2-derived constrictor prostaglandins.
- Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis.
- Characterization of GPRA, a novel G protein-coupled receptor related to asthma.
- Leukotriene inhibitors in combination with steroids: potential role in the development of primary bacterial peritonitis.
- MCI-186 (edaravone), a free radical scavenger, attenuates hepatic warm ischemia-reperfusion injury in rats.
- Efficacy and tolerability of three different doses of oral pimecrolimus in the treatment of moderate to severe atopic dermatitis: a randomized controlled trial.
- The protective effect of alpha-crystallin against acute inflammation in mice.
- IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression.
- Prevention of NF-kappaB activation in vivo by a cell-permeable NF-kappaB inhibitor peptide.
- Population pharmacokinetics of rituximab (anti-CD20 monoclonal antibody) in rheumatoid arthritis patients during a phase II clinical trial.
- APT070 (Mirococept), a membrane-localised complement inhibitor, inhibits inflammatory responses that follow intestinal ischaemia and reperfusion injury.
- New amides of 5-acylamino-3-methyl-4-isothiazolecarboxylic acid and their immunotropic activity.
- Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease.
- Discovery of 3-OH-3-methylpipecolic hydroxamates: potent orally active inhibitors of aggrecanase and MMP-13.
- Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886.
- Syntheses of NAMDA derivatives inhibiting NO production in BV-2 cells stimulated with lipopolysaccharide.
- Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo.
- Administration route- and immune cell activation-dependent tumor eradication by IL12 electrotransfer.
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