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- Heme oxygenase-1 inhibits cigarette smoke-induced increase in the tracheal mucosal permeability in guinea pigs in vivo.
- Human keratinocytes respond to interleukin-18: implication for the course of chronic inflammatory skin diseases.
- Enhancement of cell mediated immune responses using lipid depleted lentivirus as immunogen: a novel approach for inducing recognition of new viral epitopes.
- (1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: further optimisation as highly potent and selective MSK-1-inhibitors.
- Local expression of platelet-activating factor-acetylhydrolase reduces accumulation of oxidized lipoproteins and inhibits inflammation, shear stress-induced thrombosis, and neointima formation in balloon-injured carotid arteries in nonhyperlipidemic rabbits.
- The cysteine-rich region of respiratory syncytial virus attachment protein inhibits innate immunity elicited by the virus and endotoxin.
- Evasion of Toll-like receptor 5 by flagellated bacteria.
- Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein.
- Dual targeting of transformed and untransformed HTLV-1-infected T cells by DHMEQ, a potent and selective inhibitor of NF-kappaB, as a strategy for chemoprevention and therapy of adult T-cell leukemia.
- Human immunodeficiency virus type 1 Vpr impairs dendritic cell maturation and T-cell activation: implications for viral immune escape.
- Enhanced potency of plasmid DNA microparticle human immunodeficiency virus vaccines in rhesus macaques by using a priming-boosting regimen with recombinant proteins.
- Investigating the role of relaxin in the regulation of airway fibrosis in animal models of acute and chronic allergic airway disease.
- Haematopoietic stem cell transplantation in the treatment of severe autoimmune disease: results from phase I/II studies, prospective randomized trials and future directions.
- A potency assay for a replication incompetent adenovirus type 5 carrying a human fgf-4 gene.
- Toll-like receptors on tumor cells facilitate evasion of immune surveillance.
- Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines.
- Human adaptive immune system Rag2-/-gamma(c)-/- mice.
- Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin.
- IL-24 inhibits the growth of hepatoma cells in vivo.
- The cost effectiveness of infliximab for severe treatment-resistant rheumatoid arthritis in the UK.
- Rhodanine derivatives as inhibitors of JSP-1.
- A systematic approach for comprehensive T-cell epitope discovery using peptide libraries.
- Oncolytic measles virus in cutaneous T-cell lymphomas mounts antitumor immune responses in vivo and targets interferon-resistant tumor cells.
- Crystal structure of human toll-like receptor 3 (TLR3) ectodomain.
- Roflumilast fully prevents emphysema in mice chronically exposed to cigarette smoke.
- Treatment of experimental asthma by decoy-mediated local inhibition of activator protein-1.
- A prothrombin activator (Lopap) modulating inflammation, coagulation and cell survival mechanisms.
- Anthocyanidins inhibit cyclooxygenase-2 expression in LPS-evoked macrophages: structure-activity relationship and molecular mechanisms involved.
- Combined genetic and chemical capsid modifications enable flexible and efficient de- and retargeting of adenovirus vectors.
- Development of a transposon-based approach for identifying novel transgene insertion sites within the replicating adenovirus.
- Microarray analysis of tumour antigen expression in presentation acute myeloid leukaemia.
- Amphiphilic pyridinium salts block TNF alpha/NF kappa B signaling and constitutive hypersecretion of interleukin-8 (IL-8) from cystic fibrosis lung epithelial cells.
- Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice.
- Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli.
- Anti-inflammatory and antioxidative effects of propofol on lipopolysaccharide-activated macrophages.
- Antisense RNA to inducible nitric oxide synthase reduces cytokine-mediated brain endothelial cell death.
- A novel pathophysiological mechanism for osteoporosis suggested by an in vivo gene expression study of circulating monocytes.
- P2 receptor blockade attenuates fever and cytokine responses induced by lipopolysaccharide in rats.
- CXCL12 (SDF-1) and CXCL13 (BCA-1) chemokines significantly induce proliferation and collagen type I expression in osteoblasts from osteoarthritis patients.
- Attenuation of graft injury in porcine liver transplantation from non-heart beating donor by FR167653.
- Virus specific immune responses after human neoadjuvant adenovirus-mediated suicide gene therapy for prostate cancer.
- The use of a panel of monoclonal antibodies to enrich circulating breast cancer cells facilitates their detection.
- Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer.
- Anti-CD25 monoclonal antibody (basiliximab) for prevention of graft-versus-host disease after haploidentical bone marrow transplantation for hematological malignancies.
- Agonists for the peroxisome proliferator-activated receptor-alpha and the retinoid X receptor inhibit inflammatory responses of microglia.
- Increased risk of asthma attacks and emergency visits among asthma patients with allergic rhinitis: a subgroup analysis of the investigation of montelukast as a partner agent for complementary therapy [corrected]
- Characteristics of intermittent and persistent allergic rhinitis: DREAMS study group.
- Immediate transfection of patient-derived leukemia: a novel source for generating cell-based vaccines.
- Cytotoxic, antiviral (in-vitro and in-vivo), immunomodulatory activity and influence on mitotic divisions of three taxol derivatives: 10-deacetyl-baccatin III, methyl (N-benzoyl-(2'R,3'S)-3'-phenylisoserinate) and N-benzoyl-(2'R,3'S)-3'-phenylisoserine.
- Anti-inflammatory and analgesic effects of atorvastatin in a rat model of adjuvant-induced arthritis.
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