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- Mithramycin downregulates proinflammatory cytokine-induced matrix metalloproteinase gene expression in articular chondrocytes.
- Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin.
- Decreased levels of soluble receptor for advanced glycation end products in patients with rheumatoid arthritis indicating deficient inflammatory control.
- Osteoporosis in experimental postmenopausal polyarthritis: the relative contributions of estrogen deficiency and inflammation.
- Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis.
- Gene expression profile and synovial microcirculation at early stages of collagen-induced arthritis.
- Screening of an endothelial cDNA library identifies the C-terminal region of Nedd5 as a novel autoantigen in systemic lupus erythematosus with psychiatric manifestations.
- Predictive factors of acute rejection after early cyclosporine withdrawal in renal transplant recipients who receive mycophenolate mofetil: results from a prospective, randomized trial.
- Control of T helper 2 cell function and allergic airway inflammation by PKCzeta.
- Daclizumab to prevent rejection after cardiac transplantation.
- Treatment with an amyloid-beta antibody ameliorates plaque load, learning deficits, and hippocampal long-term potentiation in a mouse model of Alzheimer's disease.
- Harmful and protective roles of neutrophils in sepsis.
- Rho-associated kinase modulates myocardial inflammatory cytokine responses.
- The molecular basis for coxib inhibition of p38alpha MAP kinase.
- Synthetic studies on novel Syk inhibitors. Part 1: Synthesis and structure-activity relationships of pyrimidine-5-carboxamide derivatives.
- QSAR study on thiazole and thiadiazole analogues as antagonists for the adenosine A1 and A3 receptors.
- CD30 antigen and multiple sclerosis: CD30, an important costimulatory molecule and marker of a regulatory subpopulation of dendritic cells, is involved in the maintenance of the physiological balance between TH1/TH2 immune responses and tolerance. The role of IFNbeta-1a in the treatment of multiple sclerosis.
- Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle.
- Proasthmatic effects and mechanisms of action of the dust mite allergen, Der p 1, in airway smooth muscle.
- Bet v 1142-156 is the dominant T-cell epitope of the major birch pollen allergen and important for cross-reactivity with Bet v 1-related food allergens.
- Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21.
- Anti-CD11d antibody treatment reduces free radical formation and cell death in the injured spinal cord of rats.
- Cutaneous side-effects of kinase inhibitors and blocking antibodies.
- Chemical modification of the naphthoyl 3-position of JWH-015: in search of a fluorescent probe to the cannabinoid CB2 receptor.
- Clinical evidence for the safety of GAD65 immunomodulation in adult-onset autoimmune diabetes.
- Bradykinin B1 antagonists: SAR studies in the 2,3-diaminopyridine series.
- A quantitative structure-activity relationship study on some series of anthranilic acid-based matrix metalloproteinase inhibitors.
- Inhibition of obliterative airway disease development following heterotopic murine tracheal transplantation by costimulatory molecule blockade using anti-CD40 ligand alone or in combination with donor bone marrow.
- Elevated expression of TARC (CCL17) and MDC (CCL22) in models of cigarette smoke-induced pulmonary inflammation.
- Development of a functional cDNA array for evaluation of the Th1/Th2 balance.
- The cAMP-specific phosphodiesterase 4B mediates Abeta-induced microglial activation.
- Soluble epoxide hydrolase is a therapeutic target for acute inflammation.
- Inhibition of p38 mitogen activated protein kinase controls airway inflammation in cystic fibrosis.
- Treatment of ovalbumin-induced experimental allergic bronchitis in rats by inhaled inhibitor of secretory phospholipase A(2).
- Systemic inflammation in COPD visualised by gene profiling in peripheral blood neutrophils.
- Transforming growth factor-beta1 drives airway remodeling in cigarette smoke-exposed tracheal explants.
- Antiinflammatory effects of salmeterol after inhalation of lipopolysaccharide by healthy volunteers.
- A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates.
- Expression of mediators of renal injury in the remnant kidney of ROP mice is attenuated by cyclooxygenase-2 inhibition.
- P-Selectin-mediated acute inflammation can be blocked by chemically modified heparin, RO-heparin.
- The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor.
- Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells.
- Treatment with tumor necrosis factor blockers is associated with a lower incidence of first cardiovascular events in patients with rheumatoid arthritis.
- Longterm safety, efficacy, and radiographic outcome with etanercept treatment in patients with early rheumatoid arthritis.
- Safety study of intraarticular injection of interleukin 1 receptor antagonist in patients with painful knee osteoarthritis: a multicenter study.
- Treatment of orbital myositis with adalimumab (Humira).
- Cell permeable peptide of JNK inhibitor prevents islet apoptosis immediately after isolation and improves islet graft function.
- Rosiglitazone protects against cyclosporine-induced pancreatic and renal injury in rats.
- S-2474, a novel nonsteroidal anti-inflammatory drug, rescues cortical neurons from human group IIA secretory phospholipase A(2)-induced apoptosis.
- Capsazepine, a vanilloid receptor antagonist, inhibits allergen-induced tracheal contraction.
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