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- Protective role for cytosolic phospholipase A2alpha in autoimmune diabetes of mice.
- Functional expression of the P2Y14 receptor in murine T-lymphocytes.
- Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures.
- Deflazacort modulates the fibrinolytic pattern and reduces uPA-dependent chemioinvasion and proliferation in rheumatoid arthritis synoviocytes.
- Targeted deletion of Fgl-2/fibroleukin in the donor modulates immunologic response and acute vascular rejection in cardiac xenografts.
- Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease.
- Anti-TNF-alpha antibody Infliximab and glucocorticoids reduce serum vascular endothelial growth factor levels in patients with rheumatoid arthritis: a pilot study.
- Inhibitory effect of whole bee venom in adjuvant-induced arthritis.
- Adamantyl cannabinoids: a novel class of cannabinergic ligands.
- Selective substrate-based inhibitors of mammalian dimethylarginine dimethylaminohydrolase.
- New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A3 adenosine receptor antagonists.
- Nonionic amphiphilic block copolymers promote gene transfer to the lung.
- Whole genome association study of rheumatoid arthritis using 27 039 microsatellites.
- The simultaneous blockade of chemokine receptors CCR2, CCR5 and CXCR3 by a non-peptide chemokine receptor antagonist protects mice from dextran sodium sulfate-mediated colitis.
- Attenuated pathogenesis of polymicrobial peritonitis in mice after TLR2 agonist pre-treatment involves ST2 up-regulation.
- In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1.
- Structure-based design and synthesis of novel non-zinc chelating MMP-12 inhibitors.
- Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory agents.
- Ikappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthma.
- Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs.
- In vivo hydrodynamic delivery of cDNA encoding IL-2: rapid, sustained redistribution, activation of mouse NK cells, and therapeutic potential in the absence of NKT cells.
- IL-4 inhibits bone-resorbing activity of mature osteoclasts by affecting NF-kappa B and Ca2+ signaling.
- Anti-vascular endothelial growth factor gene therapy attenuates lung injury and fibrosis in mice.
- A non-glycosaminoglycan-binding variant of CC chemokine ligand 7 (monocyte chemoattractant protein-3) antagonizes chemokine-mediated inflammation.
- Mucosal B cell deficiency in IgA-/- mice abrogates the development of allergic lung inflammation.
- Rapid effects of rosiglitazone treatment on endothelial function and inflammatory biomarkers.
- Inhibition of lipopolysaccharide-induced inflammatory responses by an apolipoprotein AI mimetic peptide.
- Selective inhibition of Fcepsilon RI-mediated mast cell activation by a truncated variant of Cbl-b related to the rat model of type 1 diabetes mellitus.
- Effects of repeated antigen exposure on endothelin-1-induced bronchial smooth muscle contraction and activation of RhoA in sensitized rats.
- Inhibition of acute and chronic allograft rejection in mouse models by BXL-628, a nonhypercalcemic vitamin D receptor agonist.
- Identification of potent and selective MMP-13 inhibitors.
- Regulation of neuronal P53 activity by CXCR 4.
- Group IB secretory phospholipase A2 stimulates leukotriene B4 production by a unique mechanism in human neutrophils.
- HIV-1 Viral protein-r (Vpr) protects against lethal superantigen challenge while maintaining homeostatic T cell levels in vivo.
- Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.
- Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis.
- HIF-1alpha expression regulates the bactericidal capacity of phagocytes.
- HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation.
- Effects of S21403 (mitiglinide) on postprandial generation of oxidative stress and inflammation in type 2 diabetic patients.
- In vivo effects of tepoxalin, an inhibitor of cyclooxygenase and lipoxygenase, on prostanoid and leukotriene production in dogs with chronic osteoarthritis.
- Up-regulation of cyclooxygenase-2 during acute human renal allograft rejection.
- Effects of the terminal charges in human neutrophil alpha-defensin 2 on its bactericidal and membrane activity.
- Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine.
- The neuropeptide neuromedin U promotes inflammation by direct activation of mast cells.
- Collagen and aggrecan degradation is blocked in interleukin-1-treated cartilage explants by an inhibitor of IkappaB kinase through suppression of metalloproteinase expression.
- Neutrophil depletion inhibits experimental abdominal aortic aneurysm formation.
- A prospective trial of infliximab therapy for refractory uveitis: preliminary safety and efficacy outcomes.
- The impact of major depressive disorder on the short- and long-term outcome of Crohn's disease treatment with infliximab.
- Safety and tolerability of antagonist anti-human CD40 Mab ch5D12 in patients with moderate to severe Crohn's disease.
- The beta2 integrin CD11c distinguishes a subset of cytotoxic pulmonary T cells with potent antiviral effects in vitro and in vivo.
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