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- Frontline: Inhibition of allergen-induced pulmonary inflammation by the tripeptide feG: a mimetic of a neuro-endocrine pathway.
- Ameliorating effect of hepatocyte growth factor on inflammatory bowel disease in a murine model.
- IL-7 exacerbates chronic colitis with expansion of memory IL-7Rhigh CD4+ mucosal T cells in mice.
- Phase I trial of a murine antibody to MUC1 in patients with metastatic cancer: evidence for the activation of humoral and cellular antitumor immunity.
- Macrophage inhibitor, semapimod, reduces tumor necrosis factor-alpha in myocardium in a rat model of ischemic heart failure.
- An orally active matrix metalloproteinase inhibitor, ONO-4817, reduces dextran sulfate sodium-induced colitis in mice.
- Altered airway responsiveness in CD38-deficient mice.
- Syk tyrosine kinase participates in beta1-integrin signaling and inflammatory responses in airway epithelial cells.
- Inhaled p38alpha mitogen-activated protein kinase antisense oligonucleotide attenuates asthma in mice.
- A novel mechanism for TNF-alpha regulation by p38 MAPK: involvement of NF-kappa B with implications for therapy in rheumatoid arthritis.
- NF-kappa B activation in airways modulates allergic inflammation but not hyperresponsiveness.
- Inhibition of fractalkine ameliorates murine collagen-induced arthritis.
- Impact of interleukin-6 on plaque development and morphology in experimental atherosclerosis.
- Redirecting the humoral immune response against Streptococcus mutans antigen P1 with monoclonal antibodies.
- Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity.
- Control of inflammatory pain by chemokine-mediated recruitment of opioid-containing polymorphonuclear cells.
- Long-term efficacy and safety of etanercept after readministration in patients with active ankylosing spondylitis.
- IL-13 may mediate allergen-induced hyperresponsiveness independently of IL-5 or eotaxin by effects on airway smooth muscle.
- Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
- Neutralization profiles of newly transmitted human immunodeficiency virus type 1 by monoclonal antibodies 2G12, 2F5, and 4E10.
- The discovery of orally active triaminotriazine aniline amides as inhibitors of p38 MAP kinase.
- Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases.
- Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling.
- Monoclonal antibody hNM01 in HIV-infected patients: a phase I study.
- Generation of a synthetic lymphoid tissue-like organoid in mice.
- ING-1, a monoclonal antibody targeting Ep-CAM in patients with advanced adenocarcinomas.
- Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene--amplified breast cancer cells.
- Use of abciximab prior to primary angioplasty in STEMI results in early recanalization of the infarct-related artery and improved myocardial tissue reperfusion - results of the Austrian multi-centre randomized ReoPro-BRIDGING Study.
- Dual HER 1-2 targeting of hormone-refractory prostate cancer by ZD1839 and trastuzumab.
- Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association.
- Artificial cell microcapsule for oral delivery of live bacterial cells for therapy: design, preparation, and in-vitro characterization.
- Toll-like receptor 4 or 2 agonists decrease allergic inflammation.
- Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition.
- Relationship between adherence to inhaled corticosteroids and poor outcomes among adults with asthma.
- Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma.
- Critical role for galectin-3 in airway inflammation and bronchial hyperresponsiveness in a murine model of asthma.
- Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis.
- A new NF-kappaB inhibitor attenuates a TH1 type immune response in a murine model.
- Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3,3-diphenylpropyl)-piperidinyl amides and ureas.
- Identified a morpholinyl-4-piperidinylacetic acid derivative as a potent oral active VLA-4 antagonist.
- 2,3-Diphenylpropionic acids as potent VLA-4 antagonists.
- New cyclooxygenase-2 inhibitor DFU regulates vascular endothelial growth factor expression in rheumatoid synoviocytes.
- Sirolimus-eluting vs uncoated stents for prevention of restenosis in small coronary arteries: a randomized trial.
- In vivo and in vitro roles of IL-21 in inflammation.
- Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation.
- Atorvastatin inhibits autoreactive B cell activation and delays lupus development in New Zealand black/white F1 mice.
- Synthesis and activity of substituted 4-(indazol-3-yl)phenols as pathway-selective estrogen receptor ligands useful in the treatment of rheumatoid arthritis.
- 2,3-diaminopyridine bradykinin B1 receptor antagonists.
- Novel 2-(substituted phenyl)benzimidazole derivatives with potent activity against IgE, cytokines, and CD23 for the treatment of allergy and asthma.
- Development of the "Cell Chip": a new in vitro alternative technique for immunotoxicity testing.
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