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- Respiratory tolerance is inhibited by the administration of corticosteroids.
- Protein kinase Ctheta controls Th1 cells in experimental autoimmune encephalomyelitis.
- Enhancement of adenovirus-mediated gene delivery to rheumatoid arthritis synoviocytes and synovium by fiber modifications: role of arginine-glycine-aspartic acid (RGD)- and non-RGD-binding integrins.
- Tolerogenic treatment of lupus mice with consensus peptide induces Foxp3-expressing, apoptosis-resistant, TGFbeta-secreting CD8+ T cell suppressors.
- Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade.
- Where CD4+CD25+ T reg cells impinge on autoimmune diabetes.
- Grafting aminocyclopentane carboxylic acids onto the RGD tripeptide sequence generates low nanomolar alphaVbeta3/alphaVbeta5 integrin dual binders.
- Ganciclovir and acyclovir reduce the risk of post-transplant lymphoproliferative disorder in renal transplant recipients.
- Effect of anti-CD 20 antibody rituximab in patients with post-transplant lymphoproliferative disorder (PTLD).
- Long-term cardiac outcomes in renal transplant recipients receiving fluvastatin: the ALERT extension study.
- 9-Cis-retinoic acid suppresses inflammatory responses of microglia and astrocytes.
- Synthesis of 2,5-thiazole butanoic acids as potent and selective alpha(v)beta3 integrin receptor antagonists with improved oral pharmacokinetic properties.
- Soluble CD40 ligand levels in patients with hypertension.
- Anti-proliferative and anti-inflammatory effects of topical MAPK inhibition in arterialized vein grafts.
- Effect of treating allergic rhinitis with corticosteroids in patients with mild-to-moderate persistent asthma.
- Factors associated with medication nonadherence in patients with COPD.
- Prostaglandin E2 receptor selective agonists E-prostanoid 2 and E-prostanoid 4 may have therapeutic effects on ovalbumin-induced bronchoconstriction.
- Activation of invariant NK T cells protects against experimental rheumatoid arthritis by an IL-10-dependent pathway.
- Efficacy and tolerability of oral iron therapy in inflammatory bowel disease: a prospective, comparative trial.
- p38 mitogen activated protein kinase mediates both death signaling and functional depression in the heart.
- Neutrophils and macrophages promote angiogenesis in the early stage of endometriosis in a mouse model.
- Therapeutic effect of anti-TNF-alpha antibodies in an experimental model of anti-neutrophil cytoplasm antibody-associated systemic vasculitis.
- Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination.
- On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes.
- Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditure.
- Respiratory syncytial virus-inducible BCL-3 expression antagonizes the STAT/IRF and NF-kappaB signaling pathways by inducing histone deacetylase 1 recruitment to the interleukin-8 promoter.
- Intercellular adhesion molecule-1 inhibition attenuates neurologic and hepatic damage after resuscitation in mice.
- Preliminary observations of oral nicotine therapy for inflammatory bowel disease: an open-label phase I-II study of tolerance.
- Effects of angiotensin II receptor blockade with valsartan on pro-inflammatory cytokines in patients with essential hypertension.
- Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response.
- Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6.
- Activators of viral gene expression in polarized epithelial monolayers identified by rapid-throughput drug screening.
- Rosiglitazone, an agonist of peroxisome proliferator-activated receptor gamma, reduces pulmonary inflammatory response in a rat model of endotoxemia.
- New and improved glucocorticoid receptor ligands.
- Patient-reported outcomes of psoriasis improvement with etanercept therapy: results of a randomized phase III trial.
- Phosphodiesterase 3 inhibition and cough in elderly asthmatics.
- Synthesis and structure-activity relationships of 8-azabicyclo[3.2.1]octane benzylamine NK1 antagonists.
- Tricyclic pharmacophore-based molecules as novel integrin alpha(v)beta3 antagonists. Part III: synthesis of potent antagonists with alpha(v)beta3/alpha(IIb)beta3 dual activity and improved water solubility.
- Discovering novel chemical inhibitors of human cyclophilin A: virtual screening, synthesis, and bioassay.
- Novel vitamin D3 antipsoriatic antedrugs: 16-En-22-oxa-1alpha,25-(OH)2D3 analogs.
- Long term efficacy and safety of adalimumab plus methotrexate in patients with rheumatoid arthritis: ARMADA 4 year extended study.
- CD4+ T cell-independent DNA vaccination against opportunistic infections.
- Isolated pulmonary hypertension secondary to rheumatoid arthritis.
- Elevated release of sCD40L from platelets of diabetic patients by thrombin, glucose and advanced glycation end products.
- Vascular and fibrinolytic effects of intra-arterial tumour necrosis factor-alpha in patients with coronary heart disease.
- Nurr1 dependent regulation of pro-inflammatory mediators in immortalised synovial fibroblasts.
- Effects of heme oxygenase-1 inducers on established rat adjuvant arthritis.
- Heme oxygenase-1 transduction in endothelial cells causes downregulation of monocyte chemoattractant protein-1 and of genes involved in inflammation and growth.
- Carbon monoxide reduces the expression and activity of matrix metalloproteinases 1 and 2 in alveolar epithelial cells.
- Tricyclic pharmacophore-based molecules as novel integrin alpha(v)beta3 antagonists. Part 1: design and synthesis of a lead compound exhibiting alpha(v)beta3/alpha(IIb)beta3 dual antagonistic activity.
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