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- Tricyclic pharmacophore-based molecules as novel integrin alpha(v)beta3 antagonists. Part 2: synthesis of potent alpha(v)beta3/alpha(IIb)beta3 dual antagonists.
- New 1,3,4-thiadiazole derivatives endowed with analgesic and anti-inflammatory activities.
- Relation of inflammation to peripheral arterial disease in the national health and nutrition examination survey, 1999-2002.
- Treatment with PARP-1 inhibitors, GPI 15427 or GPI 16539, ameliorates intestinal damage in rat models of colitis and shock.
- p53 protein transduction therapy: successful targeting and inhibition of the growth of the bladder cancer cells.
- Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys.
- Selective phosphodiesterase 4 inhibitors in the treatment of allergy and inflammation.
- AWD-12-281 (inhaled) (elbion/GlaxoSmithKline).
- Interleukin-4 (IL4) and Interleukin-4 receptor (IL4RA) polymorphisms in asthma: a case control study.
- Preferential inhibition of human phosphodiesterase 4 by ibudilast.
- Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction.
- Resolution of airway inflammation and hyperreactivity after in vivo transfer of CD4+CD25+ regulatory T cells is interleukin 10 dependent.
- CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function.
- Targeted deletion of integrin-linked kinase reveals a role in T-cell chemotaxis and survival.
- Anti-CD2 monoclonal antibody and tacrolimus in adult liver transplantation.
- Effects of JAK3 inhibition with CP-690,550 on immune cell populations and their functions in nonhuman primate recipients of kidney allografts.
- Effect of FTY720 on chronic cyclosporine nephropathy in rats.
- Sirolimus monotherapy: feasible immunosuppression for long-term follow-up of kidney transplantation--a pilot experience.
- Reduction of experimental colitis in the rat by inhibitors of glycogen synthase kinase-3beta.
- Microarray and bioinformatic detection of novel and established genes expressed in experimental anti-Thy1 nephritis.
- Biochemical monitoring of mTOR inhibitor-based immunosuppression following kidney transplantation: a novel approach for tailored immunosuppressive therapy.
- Induction of protective genes by cobalt ameliorates tubulointerstitial injury in the progressive Thy1 nephritis.
- Critical role for monocyte chemoattractant protein-1 and macrophage inflammatory protein-1alpha in induction of experimental autoimmune myocarditis and effective anti-monocyte chemoattractant protein-1 gene therapy.
- Induction of apoptosis by the Ste20-like kinase SLK, a germinal center kinase that activates apoptosis signal-regulating kinase and p38.
- Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium.
- ROLE OF ENDOGENOUS AND EXOGENOUS LIGANDS FOR THE PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR alpha IN THE DEVELOPMENT OF BLEOMYCIN-INDUCED LUNG INJURY.
- Macrophage migration inhibitory factor within the alveolar spaces induces changes in the heart during late experimental sepsis.
- Calcitonin gene-related peptide inhibits local acute inflammation and protects mice against lethal endotoxemia.
- Inhibition of nitric oxide and caspase-3 mediated apoptosis by a tetrapeptide derivative (PEP1261) in cultured synovial fibroblasts from collagen-induced arthritis.
- VIP down-regulates TLR4 expression and TLR4-mediated chemokine production in human rheumatoid synovial fibroblasts.
- Macrophages induce an allergen-specific and long-term suppression in a mouse asthma model.
- Etoricoxib in the treatment of osteoarthritis over 52-weeks: a double-blind, active-comparator controlled trial [NCT00242489].
- Autocrine role of vascular IL-15 in intimal thickening.
- Involvement of P2X receptor subtypes in ATP-induced enhancement of the cough reflex sensitivity.
- Adiponectin and inflammatory markers in peripheral arterial occlusive disease.
- In silico fragment-based discovery of DPP-IV S1 pocket binders.
- Synthesis and pharmacology of 11-nor-1-methoxy-9-hydroxyhexahydrocannabinols and 11-nor-1-deoxy-9-hydroxyhexahydrocannabinols: new selective ligands for the cannabinoid CB2 receptor.
- Microarray analysis of gene expression during the inflammation and endochondral bone formation stages of rat femur fracture repair.
- Anti-inflammatory effects of clopidogrel intake in renal transplant patients: effects on platelet-leukocyte interactions, platelet CD40 ligand expression, and proinflammatory biomarkers.
- Risk of adverse gastrointestinal outcomes in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis.
- Safety and efficacy of influenza vaccination in systemic lupus erythematosus patients with quiescent disease.
- A selective COX-2 inhibitor suppresses chronic pancreatitis in an animal model (WBN/Kob rats): significant reduction of macrophage infiltration and fibrosis.
- Protection of erythrocytes from human complement-mediated lysis by membrane-targeted recombinant soluble CD59: a new approach to PNH therapy.
- Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays.
- CD56brightCD16(-) NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation.
- Protein kinase C potentiates homologous desensitization of the beta2-adrenoceptor in bovine tracheal smooth muscle.
- A combination therapy of PEGylation and immunosuppressive agent for successful islet transplantation.
- Parathyroid hormone activates PKC-delta and regulates osteoblastic differentiation via a PLC-independent pathway.
- Differential expression of aquaporin 7 in adipose tissue of lean and obese high fat consumers.
- Simvastatin induces caspase-independent apoptosis in LPS-activated RAW264.7 macrophage cells.
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