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- Adiponectin inhibits Toll-like receptor family-induced signaling.
- The design and synthesis of YC-1 analogues as probes for soluble guanylate cyclase.
- Sesquiterpene lactones as inhibitors of IL-8 expression in HeLa cells.
- TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes.
- IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis.
- Prior anti-dsDNA antibody status does not predict later disease manifestations in systemic lupus erythematosus.
- Attenuation of experimental colonic injury by thiazolidinedione agents.
- Protein inhibitor of activated STAT3 inhibits adipogenic gene expression.
- Human genetic evidence that OX40 is implicated in myocardial infarction.
- Identification of a phenotypically and functionally distinct population of long-lived neutrophils in a model of reverse endothelial migration.
- Identification of tyrosine residues crucial for CD200R-mediated inhibition of mast cell activation.
- Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis.
- A fundamental bimodal role for neuropeptide Y1 receptor in the immune system.
- Losartan attenuates bleomycin-induced pulmonary fibrosis in rats.
- Symptom-based questionnaire for differentiating COPD and asthma.
- Symptom-based questionnaire for identifying COPD in smokers.
- RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists.
- Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models.
- A phase 2 dose-finding study of PEGylated recombinant methionyl human soluble tumor necrosis factor type I in patients with rheumatoid arthritis.
- A randomized, blinded, parallel group, placebo controlled pilot study evaluating the effect of PVAC treatment in patients with diffuse systemic sclerosis.
- The effect of apoptosis signal-regulating kinase 1 gene transfer on rat collagen induced arthritis.
- Cancer screening in patients with systemic lupus erythematosus.
- Novel Abeta peptide immunogens modulate plaque pathology and inflammation in a murine model of Alzheimer's disease.
- Expression of myo-inositol oxygenase in tissues susceptible to diabetic complications.
- Design and synthesis of a novel, achiral class of highly potent and selective, orally active neurokinin-1 receptor antagonists.
- Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors.
- Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy.
- Anti-inflammatory mechanisms of phenanthroindolizidine alkaloids.
- Airway smooth muscle excitation-contraction coupling and airway hyperresponsiveness.
- Adenoviral mediated anti-sense CD38 attenuates TNF-alpha-induced changes in calcium homeostasis of human airway smooth muscle cells.
- Polaprezinc (N-(3-aminopropionyl)-L-histidinato zinc) ameliorates dextran sulfate sodium-induced colitis in mice.
- Different stereochemical requirements for CXCR4 binding and signaling functions as revealed by an anti-HIV, D-amino acid-containing SMM-chemokine ligand.
- Human airway trypsin-like protease induces amphiregulin release through a mechanism involving protease-activated receptor-2-mediated ERK activation and TNF alpha-converting enzyme activity in airway epithelial cells.
- Amiloride derivatives enhance insulin release in pancreatic islets from diabetic mice.
- Distinct functional profiles of aripiprazole and olanzapine at RNA edited human 5-HT2C receptor isoforms.
- Mechanism of the cardioprotection of rhEPO pretreatment on suppressing the inflammatory response in ischemia-reperfusion.
- Anti-inflammatory properties of cholinergic up-regulation: A new role for acetylcholinesterase inhibitors.
- Overexpression of UCP3 in both murine and human myotubes is linked with the activation of proteolytic systems: a role in muscle wasting?
- Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: glia dictates resistance versus vulnerability to neurodegeneration.
- Inhibition of skin sclerosis by 15deoxy delta12,14-prostaglandin J2 and retrovirally transfected prostaglandin D synthase in a mouse model of bleomycin-induced scleroderma.
- Design, synthesis, and biological evaluation of substituted 3-alkylthio-4,5-diaryl-4H-1,2,4-triazoles as selective COX-2 inhibitors.
- Synthesis and appetite suppressant activity of 1-aryloxy-2-substituted aminomethyltetrahydronaphthalenes as conformationally rigid analogues of fluoxetine.
- TLR2 agonist ameliorates murine experimental allergic conjunctivitis by inducing CD4 positive T-cell apoptosis rather than by affecting the Th1/Th2 balance.
- Bromelain exerts anti-inflammatory effects in an ovalbumin-induced murine model of allergic airway disease.
- The anti-CD14 antibody IC14 suppresses ex vivo endotoxin stimulated tumor necrosis factor-alpha in patients with chronic heart failure.
- Rat models of asthma and chronic obstructive lung disease.
- A potent antiangiogenic factor, endostatin prevents the development of asthma in a murine model.
- Notch signaling: a mediator of beta-cell de-differentiation in diabetes?
- Delayed administration of erythropoietin and its non-erythropoietic derivatives ameliorates chronic murine autoimmune encephalomyelitis.
- Antagonistic effects of nobiletin, a polymethoxyflavonoid, on eosinophilic airway inflammation of asthmatic rats and relevant mechanisms.
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