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- Conversion from cyclosporine to tacrolimus after renal transplantation improves cardiovascular risk factors.
- CD40 antisense oligonucleotide inhibition of trinitrobenzene sulphonic acid induced rat colitis.
- FK778 and FK506 combination therapy to control acute rejection after rat liver allotransplantation.
- Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model.
- A new immunosuppressant, FTY720, in canine kidney transplantation: effect of single-drug, induction and combination treatments.
- Inhibitory effects of anti-CXCR4 antibodies on human colon cancer cells.
- CCR4-deficient mice show prolonged graft survival in a chronic cardiac transplant rejection model.
- NOD mice have a severely impaired ability to recruit leukocytes into sites of inflammation.
- Assessment of the efficacy of different statins in murine collagen-induced arthritis.
- Effect of intermittent administration of human parathyroid hormone on bone mineral density and arthritis in rats with collagen-induced arthritis.
- Reduced expression of transforming growth factor beta 1 exacerbates pathology in an experimental asthma model.
- Respiratory syncytial virus-induced exaggeration of allergic airway disease is dependent upon CCR1-associated immune responses.
- Synchronized infection of cell cultures by magnetically controlled virus.
- Peripheral T cell tolerance occurs early during spontaneous prostate cancer development and can be rescued by dendritic cell immunization.
- Orally active CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological activities of 1-benzazepine derivatives containing a sulfoxide moiety.
- CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological evaluation of piperidine-4-carboxamide derivatives.
- Design and synthesis of (Z)-1,2-diphenyl-1-(4-methanesulfonamidophenyl)alk-1-enes and (Z)-1-(4-azidophenyl)-1,2-diphenylalk-1-enes: novel inhibitors of cyclooxygenase-2 (COX-2) with anti-inflammatory and analgesic activity.
- Everolimus (Certican) 12-month safety and efficacy versus mycophenolate mofetil in de novo renal transplant recipients.
- Adoptive immunotherapy of prostate cancer bone lesions using redirected effector lymphocytes.
- Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium-induced colitis in mice.
- Chemokine receptor CCR2 involvement in skeletal muscle regeneration.
- Inflammatory markers and the risk of coronary heart disease in men and women.
- Synthesis and SAR of novel 4,5-diarylimidazolines as potent P2X7 receptor antagonists.
- Design and synthesis of (E)-1,1,2-triarylethenes: novel inhibitors of the cyclooxygenase-2 (COX-2) isozyme.
- Potent Kv1.3 inhibitors from correolide-modification of the C18 position.
- Intravenous CDP870, a PEGylated Fab' fragment of a humanized antitumour necrosis factor antibody, in patients with moderate-to-severe Crohn's disease: an exploratory study.
- The novel phosphodiesterase 4 inhibitor, CI-1044, inhibits LPS-induced TNF-alpha production in whole blood from COPD patients.
- A rho kinase inhibitor, Y-27632 inhibits pulmonary eosinophilia, bronchoconstriction and airways hyperresponsiveness in allergic mice.
- Antitumor immunization of head and neck squamous cell carcinoma patients with a virus-modified autologous tumor cell vaccine.
- Oral alitretinoin (9-cis-retinoic acid) therapy for chronic hand dermatitis in patients refractory to standard therapy: results of a randomized, double-blind, placebo-controlled, multicenter trial.
- Neutralizing antibodies elicited by immunization of monkeys with DNA plasmids and recombinant adenoviral vectors expressing human immunodeficiency virus type 1 proteins.
- Influence of genetic background and gender on hypertension and renal failure in COX-2-deficient mice.
- Autoimmunity in a phase I trial of a fully human anti-cytotoxic T-lymphocyte antigen-4 monoclonal antibody with multiple melanoma peptides and Montanide ISA 51 for patients with resected stages III and IV melanoma.
- Celecoxib, a selective cyclooxygenase-2 inhibitor, decreases monocyte chemoattractant protein-1 expression and neointimal hyperplasia in the rabbit atherosclerotic balloon injury model.
- Design, synthesis, and pharmacological evaluation of pyridinic analogues of nimesulide as cyclooxygenase-2 selective inhibitors.
- Design, synthesis, and biological activity of novel, potent, and selective (benzoylaminomethyl)thiophene sulfonamide inhibitors of c-Jun-N-terminal kinase.
- Insertion of an aspartic acid moiety into cyclic pseudopeptides: synthesis and biological characterization of potent antagonists for the human Tachykinin NK-2 receptor.
- Anuroctoxin, a new scorpion toxin of the alpha-KTx 6 subfamily, is highly selective for Kv1.3 over IKCa1 ion channels of human T lymphocytes.
- Effect of E6060 [4-{5-[7-fluoro-4-(trifluoromethyl)benzo[b]furan-2-yl]-1H-2-pyrrolyl}benzoic acid], a novel subtype-selective retinoid, on lupus-like nephritis in female (NZBxNZW)F1 mice.
- {beta}-Cell function following human islet transplantation for type 1 diabetes.
- Randomized controlled clinical trial of glargine versus ultralente insulin in the treatment of type 1 diabetes.
- Accurate multiplex gene synthesis from programmable DNA microchips.
- Activation of PI3K-Akt pathway mediates antiapoptotic effects of beta-adrenergic agonist in airway eosinophils.
- Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue.
- Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience.
- Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry.
- Evidence for vascular macrophage migration inhibitory factor in destabilization of human atherosclerotic plaques.
- A placebo-controlled randomized clinical trial of perioperative administration of gabapentin, rofecoxib and their combination for spontaneous and movement-evoked pain after abdominal hysterectomy.
- Treatment of lung cancer using clinically relevant oral doses of the cyclooxygenase-2 inhibitor rofecoxib: potential value as adjuvant therapy after surgery.
- Human autologous tumor-specific T-cell responses induced by liposomal delivery of a lymphoma antigen.
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