Sitemap > Breaking Research > Immunology & Inflammatory Diseases
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- Novel concepts of neuropeptide-based drug therapy: vasoactive intestinal polypeptide and its receptors.
- Inhibition of human immunodeficiency virus type 1 infection in macrophages by an alpha-v integrin blocking antibody.
- Measurement of cytokine release at the single cell level using the ELISPOT assay.
- An unexpected antibody response to an engineered influenza virus modifies CD8+ T cell responses.
- Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction.
- Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1.
- A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation.
- Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response.
- Cytidine-phosphate-guanosine oligodeoxynucleotides and interferon-alpha-expressing tumor cells effectively induce dendritic cell maturation in vitro.
- Zn-alpha2-glycoprotein, an MHC class I-related glycoprotein regulator of adipose tissues: modification or abrogation of ligand binding by site-directed mutagenesis.
- Serotonin transporter mRNA expression is decreased by lamivudine and ribavirin and increased by interferon in immune cells.
- Conversion to sirolimus and mycophenolate can attenuate the progression of bronchiolitis obliterans syndrome and improves renal function after lung transplantation.
- Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells.
- Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells.
- Budesonide/formoterol in a single inhaler for maintenance and relief in mild-to-moderate asthma: a randomized, double-blind trial.
- CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, for steroid-dependent Crohn's disease: a randomized, double-blind, placebo-controlled trial.
- Primary care physician perceptions of non-steroidal anti-inflammatory drug and aspirin-associated toxicity: results of a national survey.
- Delivery of tumor associated antigens to antigen presenting cells using penetratin induces potent immune responses.
- Dipeptide nitrile inhibitors of cathepsin K.
- Three-dimensional solution structure of EM703 with potent promoting activity of monocyte-to-macrophage differentiation.
- Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors.
- A pneumococcal pilus influences virulence and host inflammatory responses.
- Administration of PUMA adenovirus increases the sensitivity of esophageal cancer cells to anticancer drugs.
- Effects of nano particles on cytokine expression in murine lung in the absence or presence of allergen.
- The role of COX-2 inhibitors in the perioperative setting: efficacy and safety--a systematic review.
- Stem cell factor and its receptor c-Kit as targets for inflammatory diseases.
- Serum amyloid A (SAA) activates human mast cells which leads into degradation of SAA and generation of an amyloidogenic SAA fragment.
- Low molecular weight indole fragments as IMPDH inhibitors.
- Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships.
- Determinants of gastro-protective drugs co-prescription during treatment with nonselective NSAIDs: a prospective survey of 2197 patients recruited in primary care.
- Identification of P311 as a potential gene regulating alveolar generation.
- Pharmacokinetics of darbepoetin alfa after intravenous or subcutaneous administration in patients with non-myeloid malignancies undergoing chemotherapy.
- Intranasal IFNgamma extends passive IgA antibody protection of mice against Mycobacterium tuberculosis lung infection.
- Tumour necrosis factor-alpha production stimulated by heat shock protein 70 and its inhibition in circulating dendritic cells and cells eluted from mucosal tissues in Crohn's disease.
- Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases.
- Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs in the respiratory tract: potential implications in asthma and other lung diseases.
- Autoantibodies against aggrecan in systemic rheumatic diseases.
- New derivatives of xanthenone-4-acetic acid: synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells.
- Downregulation by a long-acting beta2-adrenergic receptor agonist and corticosteroid of Staphylococcus aureus-induced airway epithelial inflammatory mediator production.
- Involvement of GATA-3-dependent Th2 lymphocyte activation in airway hyperresponsiveness.
- Efficacy and tolerability of fluticasone propionate/salmeterol administered twice daily via hydrofluoroalkane 134a metered-dose inhaler in adolescent and adult patients with persistent asthma: a randomized, double-blind, placebo-controlled, 12-week study.
- Comparison between nebulized adrenaline and beta2 agonists for the treatment of acute asthma. A meta-analysis of randomized trials.
- Mycophenolate mofetil as first-line treatment improves clinically evident early scleroderma lung disease.
- Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates.
- Nitric oxide-releasing flurbiprofen reduces formation of proinflammatory hydrogen sulfide in lipopolysaccharide-treated rat.
- Neuroprotective properties of the innate immune system and bone marrow stem cells in Alzheimer's disease.
- Incidence and predictors of fractures in children after solid organ transplantation: a 5-year prospective, population-based study.
- Role of interleukin-4 in atherosclerosis.
- Involvement of a tissue-specific autoantibody in skin disorders of murine systemic lupus erythematosus and autoinflammatory diseases.
- A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways.
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