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- Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia.
- TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE.
- Regulation of peripheral T cell activation by calreticulin.
- Resistance to experimental autoimmune encephalomyelitis and impaired IL-17 production in protein kinase C theta-deficient mice.
- Vaccine-induced memory CD8+ T cells cannot prevent central nervous system virus reactivation.
- Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: the role of CD4+ T cells and IFN-gamma.
- Exacerbation of experimental autoimmune encephalomyelitis in P2X7R-/- mice: evidence for loss of apoptotic activity in lymphocytes.
- The human specific CCR1 antagonist CP-481,715 inhibits cell infiltration and inflammatory responses in human CCR1 transgenic mice.
- The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness.
- Pulmonary lipopolysaccharide (LPS)-binding protein inhibits the LPS-induced lung inflammation in vivo.
- Hydroxyl radical scavenging reactivity of proton pump inhibitors.
- Selection of a 2-azabicyclo[2.2.2]octane-based alpha4beta1 integrin antagonist as an inhaled anti-asthmatic agent.
- Denosumab in postmenopausal women with low bone mineral density.
- Interleukin-5 (IL-5) augments the progression of liver fibrosis by regulating IL-13 activity.
- Donor graft adenoviral iNOS gene transfer ameliorates rat liver transplant preservation injury and improves survival.
- Efficient synthesis of novel NK1 receptor antagonists: selective 1,4-addition of grignard reagents to 6-chloronicotinic acid derivatives.
- Generation and characterization of a humanized bradykinin B1 receptor mouse.
- Granulocyte colony-stimulating factor and stem cell factor improve endogenous repair after myocardial infarction.
- Optimization of 2-aminothiazole derivatives as CCR4 antagonists.
- Anti-immunology: evasion of the host immune system by bacterial and viral pathogens.
- Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response.
- Platelet-derived or soluble CD154 induces vascularized allograft rejection independent of cell-bound CD154.
- IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and Fc gamma RIIb cross-linking.
- Impaired virus-induced interferon-alpha2 release in adult asthmatic patients.
- 4-1 BB stimulation inhibits allergen-specific immunoglobulin E production and airway hyper-reactivity but partially suppresses bronchial eosinophilic inflammation in a mouse asthma model.
- A cyclooxygenase-2 inhibitor alters Th1/Th2 cytokine balance and suppresses autoimmune myocarditis in rats.
- Mechanism of IL-6-mediated cardiac dysfunction following trauma-hemorrhage.
- Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases.
- Scheduled maintenance treatment with infliximab is superior to episodic treatment for the healing of mucosal ulceration associated with Crohn's disease.
- Annexin 2: a novel human immunodeficiency virus type 1 Gag binding protein involved in replication in monocyte-derived macrophages.
- Innate immune responses to herpes simplex virus type 2 influence skin homing molecule expression by memory CD4+ lymphocytes.
- Reovirus delays diabetes onset but does not prevent insulitis in nonobese diabetic mice.
- Discovery of novel biaryl heterocyclic EP1 receptor antagonists.
- The Bsmoc group as a novel scaffold for the design of irreversible inhibitors of cysteine proteases.
- CD40 ligand and risk of ischemic stroke or coronary events in patients with chronic coronary heart disease.
- Enhanced expression of platelet CD40-ligand by in vitro lipopolysaccharide-challenge in patients with ventricular fibrillation complicating acute myocardial infarction.
- Cannabinoid receptor CB2 modulates the CXCL12/CXCR4-mediated chemotaxis of T lymphocytes.
- Statins: potential new indications in inflammatory conditions.
- HSV-mediated expression of interleukin-4 in dorsal root ganglion neurons reduces neuropathic pain.
- Protective effect of the DNA vaccine encoding the major house dust mite allergens on allergic inflammation in the murine model of house dust mite allergy.
- CD40 deficiency mitigates Alzheimer's disease pathology in transgenic mouse models.
- Tricyclic pharmacophore-based molecules as novel integrin alphavbeta3 antagonists. Part IV: preliminary control of alphavbeta3 selectivity by meta-oriented substitution.
- Variants of the CD40 gene but not of the CD40L gene are associated with coronary artery calcification in the Diabetes Heart Study (DHS).
- Immunomodulatory effects of IL-12 secreted by Lactococcus lactis on Th1/Th2 balance in ovalbumin (OVA)-induced asthma model mice.
- The immunostimulant RU41740 from Klebsiella pneumoniae activates human cells in whole blood to potentially stimulate innate and adaptive immune responses.
- Are American College of Rheumatology 50% response criteria superior to 20% criteria in distinguishing active aggressive treatment in rheumatoid arthritis clinical trials reported since 1997? A meta-analysis of discriminant capacities.
- Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses.
- Intensified and protective CD4+ T cell immunity in mice with anti-dendritic cell HIV gag fusion antibody vaccine.
- In vitro and in vivo nuclear factor-kappaB inhibitory effects of the cell-penetrating penetratin peptide.
- Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to intercellular adhesion molecule 1.
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