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- Caffeine-mediated enhancement of glucocorticoid receptor activity in human osteoblastic cells.
- Vasculoprotective effect of insulin in the ischemic/reperfused canine heart: role of Akt-stimulated NO production.
- Crystallographic studies on two bioisosteric analogues, N-acetyl-beta-D-glucopyranosylamine and N-trifluoroacetyl-beta-D-glucopyranosylamine, potent inhibitors of muscle glycogen phosphorylase.
- Momordin I, an inhibitor of AP-1, suppressed osteoclastogenesis through inhibition of NF-kappaB and AP-1 and also reduced osteoclast activity and survival.
- Structural basis for the GSK-3beta binding affinity and selectivity against CDK-2 of 1-(4-aminofurazan-3yl)-5-dialkylaminomethyl-1H-[1,2,3] triazole-4-carboxylic acid derivatives.
- Impact of treatment of coronary artery disease with sirolimus-eluting stents on outcomes of diabetic and nondiabetic patients.
- Incidence of end-stage renal disease in patients with type 1 diabetes.
- Effects of Brx-019 (acetic acid 3,6a,9-triacetoxy-6,6a,7, 11b-tetrahydro-indeno [2,1-c] chromen-10-yl ester), a Brazilin derivative, on T cell-mediated immune responses in multiple low dose streptozotocin-induced diabetic C57BL/6 male mice.
- Molecular docking and 3D-QSAR on 2-(oxalylamino) benzoic acid and its analogues as protein tyrosine phosphatase 1B inhibitors.
- Inhaled insulin improves glycemic control when substituted for or added to oral combination therapy in type 2 diabetes: a randomized, controlled trial.
- Exenatide versus insulin glargine in patients with suboptimally controlled type 2 diabetes: a randomized trial.
- Endothelial dysfunction in the streptozotocin-induced diabetic apoE-deficient mouse.
- Erythromycin ameliorates renal injury via anti-inflammatory effects in experimental diabetic rats.
- Evidence that the 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD1) is regulated by pentose pathway flux. Studies in rat adipocytes and microsomes.
- Heme oxygenase 1 (HO-1) regulates osteoclastogenesis and bone resorption.
- Effect of weight loss on blood pressure, arterial compliance, and insulin resistance in normotensive obese subjects.
- Glucose is a key metabolic regulator of osteoclasts; glucose stimulated increases in ATP/ADP ratio and calmodulin kinase II activity.
- Combination teriparatide and raloxifene therapy for postmenopausal osteoporosis: results from a 6-month double-blind placebo-controlled trial.
- Relationship between osteoporosis and cardiovascular disease in postmenopausal women.
- VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis.
- InDuo, a novel combined insulin injection and blood glucose monitoring device - effective and save as other devices, and patient preference.
- Genistein, EGCG, and capsaicin inhibit adipocyte differentiation process via activating AMP-activated protein kinase.
- Discovery, SAR, and X-ray structure of novel biaryl-based dipeptidyl peptidase IV inhibitors.
- Increased prevalence of third-degree atrioventricular block in patients with type II diabetes mellitus.
- Inhibition of histone deacetylase suppresses osteoclastogenesis and bone destruction by inducing IFN-beta production.
- Protection against osteoporosis by active immunization with TRANCE/RANKL displayed on virus-like particles.
- Metabolic syndrome, endothelial dysfunction, and erectile dysfunction: association and management.
- Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes.
- Obesity, peroxisome proliferator-activated receptor, and atherosclerosis in type 2 diabetes.
- Effect of muraglitazar on death and major adverse cardiovascular events in patients with type 2 diabetes mellitus.
- Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake.
- Design, synthesis, and evaluation of 2-alkoxydihydrocinnamates as PPAR agonists.
- Aplysamine-1 and related analogs as histamine H3 receptor antagonists.
- Substituted 4-hydroxyphenyl sulfonamides as pathway-selective estrogen receptor ligands.
- A free radical scavenger but not FGF-2-mediated angiogenic therapy rescues myonephropathic metabolic syndrome in severe hindlimb ischemia.
- The effect of short-contact topical tretinoin therapy for foot ulcers in patients with diabetes.
- Where CD4+CD25+ T reg cells impinge on autoimmune diabetes.
- Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K.
- Lysosomotropism of basic cathepsin K inhibitors contributes to increased cellular potencies against off-target cathepsins and reduced functional selectivity.
- Mono- or diphenylpyridazines connected to N-(2,4-difluorophenyl)-N'-heptylurea as acyl-CoA:cholesterol acyltransferase inhibitors.
- Thyroid receptor ligands. Part 4: 4'-amido bioisosteric ligands selective for the thyroid hormone receptor beta.
- Bicyclic and tricyclic thiophenes as protein tyrosine phosphatase 1B inhibitors.
- Cells expressing the stem cell factor receptor, c-kit, contribute to neoangiogenesis in diabetes.
- Effect of diabetes on the mechanisms of intrathecal antinociception of sildenafil in rats.
- Ghrelin improves renal function in mice with ischemic acute renal failure.
- Peripheral hyperinsulinemia promotes tau phosphorylation in vivo.
- Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination.
- On the edge of autoimmunity: T-cell stimulation by steady-state dendritic cells prevents autoimmune diabetes.
- Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through non-platelet-mediated effects.
- The lack of beta-adrenoceptors results in enhanced insulin sensitivity in mice exhibiting increased adiposity and glucose intolerance.
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