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- Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditure.
- Resistance to diet-induced obesity in mu-opioid receptor-deficient mice: evidence for a "thrifty gene".
- Diabetic microangiopathy in ischemic limb is a disease of disturbance of the platelet-derived growth factor-BB/protein kinase C axis but not of impaired expression of angiogenic factors.
- Short-term pioglitazone treatment improves vascular function irrespective of metabolic changes in patients with type 2 diabetes.
- Pomegranate flower extract diminishes cardiac fibrosis in Zucker diabetic fatty rats: modulation of cardiac endothelin-1 and nuclear factor-kappaB pathways.
- The protein kinase C-beta inhibitor, ruboxistaurin, for the treatment of diabetic microvascular complications.
- Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRgamma.
- Effect on insulin sensitivity of Implanon vs. GnRH agonist in women with endometriosis.
- Impact of diabetes on 12-month outcomes following coronary artery bypass graft surgery: results from the ROSETTA-CABG Registry.
- Statin therapy in Canadian patients with hypercholesterolemia: the Canadian Lipid Study -- Observational (CALIPSO).
- Improvement of glucose tolerance in type 2 diabetic patients: traditional vs. modern insulin regimens (results from the Austrian Biaspart Study).
- Efficacy and safety of insulin glulisine in patients with type 1 diabetes.
- Elevated release of sCD40L from platelets of diabetic patients by thrombin, glucose and advanced glycation end products.
- Insulin improves the endothelium-independent relaxation and the contractile response in aorta from hypertensive diabetic rats.
- Heme oxygenase-1 gene expression increases vascular relaxation and decreases inducible nitric oxide synthase in diabetic rats.
- Assessment of anti-estrogenic activity of tamoxifen in transgenic mice expressing an enhanced green fluorescent protein gene regulated by estrogen response element.
- Androstenediol analogs as ER-beta-selective SERMs.
- Decreased survival in diabetic patients with heart failure due to systolic dysfunction.
- The ruthenium-based nitric oxide scavenger, AMD6221, augments cardiovascular responsiveness to noradrenaline in rats with streptozotocin-induced diabetes.
- Does diabetes mellitus abolish the beneficial effect of primary coronary angioplasty on long-term risk of reinfarction after acute ST-segment elevation myocardial infarction compared with fibrinolysis? (A DANAMI-2 substudy).
- Hospitalizations for new heart failure among subjects with diabetes mellitus in the RENAAL and LIFE studies.
- Long-term renoprotective effects of standard versus high doses of telmisartan in hypertensive nondiabetic nephropathies.
- Underuse of ACE inhibitors and angiotensin II receptor blockers in elderly patients with diabetes.
- Pharmacological interventions that directly stimulate or modulate insulin secretion from pancreatic beta-cell: implications for the treatment of type 2 diabetes.
- Hormone replacement therapy is associated with decreased survival in women with lung cancer.
- Glucose concentration-dependent potentiation of insulin secretion by a new chemical entity, KCP256.
- A new variant in the human Kv1.3 gene is associated with low insulin sensitivity and impaired glucose tolerance.
- The effect of systemic leptin administration on aorta smooth muscle responses in diabetic rats.
- Role of renal nitric oxide synthase in diabetic kidney disease during the chronic phase of diabetes.
- Administration-route and gender-independent long-term therapeutic correction of phenylketonuria (PKU) in a mouse model by recombinant adeno-associated virus 8 pseudotyped vector-mediated gene transfer.
- Prevalence of antiplatelet therapy in patients with diabetes.
- Cystatin B as an intracellular modulator of bone resorption.
- In silico fragment-based discovery of DPP-IV S1 pocket binders.
- Synthesis and pharmacology of 11-nor-1-methoxy-9-hydroxyhexahydrocannabinols and 11-nor-1-deoxy-9-hydroxyhexahydrocannabinols: new selective ligands for the cannabinoid CB2 receptor.
- Glucose-sensing mechanisms in pancreatic beta-cells.
- Impact of insulin antibodies on insulin aspart pharmacokinetics and pharmacodynamics after 12-week treatment with multiple daily injections of biphasic insulin aspart 30 in patients with type 1 diabetes.
- Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors.
- Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage.
- Mice lacking ghrelin receptors resist the development of diet-induced obesity.
- Absence of ghrelin protects against early-onset obesity.
- Impact of rosiglitazone on beta-cell function, insulin resistance, and adiponectin concentrations: results from a double-blind oral combination study with glimepiride.
- Benzothiazole derivatives as novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1.
- Parathyroid hormone activates PKC-delta and regulates osteoblastic differentiation via a PLC-independent pathway.
- Differential expression of aquaporin 7 in adipose tissue of lean and obese high fat consumers.
- Effect of SR58611A, a potent beta-3 adrenoceptor agonist, on cutaneous wound healing in diabetic and obese mice.
- Activity and expression of semicarbazide-sensitive benzylamine oxidase in a rodent model of diabetes: interactive effects with methylamine and alpha-aminoguanidine.
- Adiponectin inhibits Toll-like receptor family-induced signaling.
- Fat storage in adipocytes requires inactivation of leptin's paracrine activity: implications for treatment of human obesity.
- TFE3 transcriptionally activates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes.
- Protein inhibitor of activated STAT3 inhibits adipogenic gene expression.
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