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- Experimental Peptide Identification Repository (EPIR): an integrated peptide-centric platform for validation and mining of tandem mass spectrometry data.
- Cancer cachexia is regulated by selective targeting of skeletal muscle gene products.
- Characteristics of US adults with the metabolic syndrome and therapeutic implications.
- Outcomes of initiation of therapy with once-daily combination of a thiazolidinedione and a biguanide at an early stage of type 2 diabetes.
- Effects of orlistat on obesity-related diseases - a six-month randomized trial.
- In vitro and in vivo evaluation of a melamine dendrimer as a vehicle for drug delivery.
- Pregabalin for the treatment of painful diabetic peripheral neuropathy: a double-blind, placebo-controlled trial.
- Venlafaxine extended release in the treatment of painful diabetic neuropathy: a double-blind, placebo-controlled study.
- Intranasal insulin improves memory in humans.
- Novel diacylglycerol kinase inhibitor selectively suppressed an U46619-induced enhancement of mouse portal vein contraction under high glucose conditions.
- Nephroprotection in Zucker diabetic fatty rats by vasopeptidase inhibition is partly bradykinin B2 receptor dependent.
- Prior statin therapy is associated with a decreased rate of severe sepsis.
- Short-term intermittent exposure to diazoxide improves functional performance of beta-cells in a high-glucose environment.
- Impaired activation of protein kinase C-zeta by insulin and phosphatidylinositol-3,4,5-(PO4)3 in cultured preadipocyte-derived adipocytes and myotubes of obese subjects.
- Absolute risk of childhood-onset type 1 diabetes defined by human leukocyte antigen class II genotype: a population-based study in the United Kingdom.
- Liver-selective glucocorticoid antagonists: a novel treatment for type 2 diabetes.
- Identification of structurally diverse growth hormone secretagogue agonists by virtual screening and structure-activity relationship analysis of 2-formylaminoacetamide derivatives.
- Adenoviral-mediated expression of porphobilinogen deaminase in liver restores the metabolic defect in a mouse model of acute intermittent porphyria.
- A vitamin D analog down-regulates proinflammatory chemokine production by pancreatic islets inhibiting T cell recruitment and type 1 diabetes development.
- Pharmacokinetic changes of DA-8159, a new erectogenic, after intravenous and oral administration to rats with diabetes mellitus induced by streptozotocin.
- Regulation of bone mass and bone turnover by neuronal nitric oxide synthase.
- Small-molecule insulin mimetic reduces hyperglycemia and obesity in a nongenetic mouse model of type 2 diabetes.
- Small interfering RNA-induced transcriptional gene silencing in human cells.
- Insulin analogues (insulin detemir and insulin aspart) versus traditional human insulins (NPH insulin and regular human insulin) in basal-bolus therapy for patients with type 1 diabetes.
- Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1 diabetes.
- Prevention of sensory disorders in diabetic Sprague-Dawley rats by aldose reductase inhibition or treatment with ciliary neurotrophic factor.
- Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy.
- Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors.
- Nifedipine retard was as effective as angiotensin converting enzyme inhibitors in preventing cardiac events in high-risk hypertensive patients with diabetes and coronary artery disease: the Japan Multicenter Investigation for Cardiovascular Diseases-B (JMIC-B) subgroup analysis.
- Effects of telmisartan compared with eprosartan on blood pressure control, glucose metabolism and lipid profile in hypertensive, type 2 diabetic patients: a randomized, double-blind, placebo-controlled 12-month study.
- Possible role of VEGF in the progression of kidney disease in streptozotocin (STZ)-induced diabetic rats: effects of an ACE inhibitor and an angiotensin II receptor antagonist.
- GUIDE study: double-blind comparison of once-daily gliclazide MR and glimepiride in type 2 diabetic patients.
- Low-dose growth hormone and human immunodeficiency virus-associated lipodystrophy syndrome: a pilot study.
- Differential expression of 5-HT(2A) and 5-HT(2C) receptor mRNAs in mice prone, or resistant, to chronic high-fat diet-induced obesity.
- Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity.
- Rofecoxib decreases renal injury in obese Zucker rats.
- Comparison of the pharmacological effects of a novel selective androgen receptor modulator, the 5alpha-reductase inhibitor finasteride, and the antiandrogen hydroxyflutamide in intact rats: new approach for benign prostate hyperplasia.
- Functional immunomics: microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes.
- Does albuminuria predict cardiovascular outcome on treatment with losartan versus atenolol in hypertension with left ventricular hypertrophy? A LIFE substudy.
- Long-term protection of obese Zucker rat kidneys from fibrosis and renal failure with an angiotensin-converting enzyme inhibitor/diuretic combination.
- HMG-CoA reductase inhibitors and the risk of vertebral fracture.
- Safety and efficacy of a novel salmon calcitonin (sCT) technology-based oral formulation in healthy postmenopausal women: acute and 3-month effects on biomarkers of bone turnover.
- Short- and long-term effects of interleukin-2 on weight, food intake, and hedonic mechanisms in the rat.
- Foxa2 regulates multiple pathways of insulin secretion.
- Mature high-affinity immune responses to (pro)insulin anticipate the autoimmune cascade that leads to type 1 diabetes.
- Portal infusion of a selective serotonin reuptake inhibitor enhances hepatic glucose disposal in conscious dogs.
- Dipeptide boronic acid, a novel proteasome inhibitor, prevents islet-allograft rejection.
- Prolonged glucose normalization of streptozotocin-induced diabetic mice by transplantation of rat islets coencapsulated with crosslinked hemoglobin.
- Insulin therapy for type 2 diabetes: rescue, augmentation, and replacement of beta-cell function.
- HMG-CoA reductase inhibitors prevent bone loss in patients with Type 2 diabetes mellitus.
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