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- Spironolactone prevents diabetic nephropathy through an anti-inflammatory mechanism in type 2 diabetic rats.
- New-onset type-2 diabetes associated with atypical antipsychotic medications.
- Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain.
- Efficacy of lipid lowering drug treatment for diabetic and non-diabetic patients: meta-analysis of randomised controlled trials.
- Intranasal vaccination with proinsulin DNA induces regulatory CD4+ T cells that prevent experimental autoimmune diabetes.
- Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo.
- PEGylated glucagon-like peptide-1 displays preserved effects on insulin release in isolated pancreatic islets and improved biological activity in db/db mice.
- Cilostazol protects diabetic rats from vascular inflammation via nuclear factor-kappa B-dependent down-regulation of vascular cell adhesion molecule-1 expression.
- Effect of 6-month calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial.
- Prevalence of overweight and obesity in the United States, 1999-2004.
- Effects of DGAT1 deficiency on energy and glucose metabolism are independent of adiponectin.
- Obese patients have lower B-type and atrial natriuretic peptide levels compared with nonobese.
- Molecular properties and preclinical pharmacology of JNJ-1250132, a steroidal progesterone receptor modulator that inhibits binding of the receptor to DNA in vitro.
- A nonprostanoid EP4 receptor selective prostaglandin E2 agonist restores bone mass and strength in aged, ovariectomized rats.
- A single transplantation of the islets can produce glycemic stability and reduction of basal insulin requirement.
- Anemia is an independent risk for mortality after acute myocardial infarction in patients with and without diabetes.
- Preventive and therapeutic potential of p38 alpha-selective mitogen-activated protein kinase inhibitor in nonobese diabetic mice with type 1 diabetes.
- Effects of calcium-sensing receptor on the secretion of parathyroid hormone-related peptide and its impact on humoral hypercalcemia of malignancy.
- CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.
- Role of the kinin B1 receptor in insulin homeostasis and pancreatic islet function.
- Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells.
- Identification of a Ca2+-ATPase in brown adipose tissue mitochondria: regulation of thermogenesis by ATP and Ca2+.
- Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes.
- Anthranilic acid based CCK1 receptor antagonists and CCK-8 have a common step in their "receptor desmodynamic processes".
- 2,4-diaminopyrimidine derivatives as potent growth hormone secretagogue receptor antagonists.
- New NO-releasing pharmacodynamic hybrids of losartan and its active metabolite: design, synthesis, and biopharmacological properties.
- Neuropeptide Y (NPY) Y4 receptor selective agonists based on NPY(32-36): development of an anorectic Y4 receptor selective agonist with picomolar affinity.
- Atorvastatin and diabetic vascular complications.
- Non-covalent cathepsin K inhibitors for the treatment of osteoporosis.
- Targeting type 1 diabetes before and at the clinical onset of disease.
- Costimulation and autoimmune diabetes in BB rats.
- FATP1 is an insulin-sensitive fatty acid transporter involved in diet-induced obesity.
- Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 reduces food intake and weight gain but maintains energy expenditure in diet-induced obese mice.
- Effects of early statin treatment on symptomatic heart failure and ischemic events after acute myocardial infarction in Japanese.
- DITPA restores the repolarizing potassium currents Itof and Iss in cardiac ventricular myocytes of diabetic rats.
- Benzo[b]thiophene-2-carboxamides and benzo[b]furan-2-carboxamides are potent antagonists of the human H3-receptor.
- Diphenylmethane skeleton as a multi-template for nuclear receptor ligands: preparation of FXR and PPAR ligands.
- Restoring depressed HERG K+ channel function as a mechanism for insulin treatment of abnormal QT prolongation and associated arrhythmias in diabetic rabbits.
- Does hyperglycemia reduce proliferation or increase apoptosis?
- The prevalence of co-morbid depression in adults with Type 1 diabetes: systematic literature review.
- Effects of gender difference on cardiac myocyte dysfunction in streptozotocin-induced diabetic rats.
- Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation.
- Structure-based drug design of a novel family of PPARgamma partial agonists: virtual screening, X-ray crystallography, and in vitro/in vivo biological activities.
- Biarylaniline phenethanolamines as potent and selective beta3 adrenergic receptor agonists.
- (S)-4,5-dihydro-2-(2-hydroxy-4-hydroxyphenyl)-4-methyl-4-thiazolecarboxylic acid polyethers: a solution to nephrotoxicity.
- Synthesis and structure-activity relationship study of antidiabetic penta-O-galloyl-D-glucopyranose and its analogues.
- Effect of BMP-2 gene transfer on bone healing in sheep.
- Effects of streptozotocin-induced diabetes on bladder and erectile (dys)function in the same rat in vivo.
- 2-(8-hydroxy-6-methoxy-1-oxo-1h-2-benzopyran-3-yl) propionic acid, an inhibitor of angiogenesis, ameliorates renal alterations in obese type 2 diabetic mice.
- Effect of mirtazapine treatment on body composition and metabolism.
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