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- Impact of low high-density lipoproteins on in-hospital events and one-year clinical outcomes in patients with non-ST-elevation myocardial infarction acute coronary syndrome treated with drug-eluting stent implantation.
- Effect of diabetes mellitus on five-year clinical outcomes after single-vessel coronary stenting (a pooled analysis of coronary stent clinical trials).
- Medium-chain fatty acids as ligands for orphan G protein-coupled receptor GPR84.
- Evolving resistance to obesity in an insect.
- Direct demonstration of an antiinflammatory effect of simvastatin in subjects with the metabolic syndrome.
- Association of hormonal dysregulation with metabolic syndrome in older women: data from the InCHIANTI study.
- Effects of pioglitazone and metformin on beta-cell function in nondiabetic subjects at high risk for type 2 diabetes.
- Spontaneously reduced blood pressure load in the rat streptozotocin-induced diabetes model: potential pathogenetic relevance.
- An open-label pilot study of the combination therapy of metformin and fluoxetine for weight reduction.
- Darbepoetin alfa administration to achieve and maintain target hemoglobin levels for 1 year in patients with chronic kidney disease.
- Design and synthesis of dual peroxisome proliferator-activated receptors gamma and delta agonists as novel euglycemic agents with a reduced weight gain profile.
- Iminosugars as potential inhibitors of glycogenolysis: structural insights into the molecular basis of glycogen phosphorylase inhibition.
- Combined costimulation blockade prevents rejection of allogeneic islets in mice.
- Atypical antipsychotics related metabolic syndrome in bipolar patients.
- Aberrant hepatic expression of PPARgamma2 stimulates hepatic lipogenesis in a mouse model of obesity, insulin resistance, dyslipidemia, and hepatic steatosis.
- Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice.
- Pyridine-3-propanoic acids: Discovery of dual PPARalpha/gamma agonists as antidiabetic agents.
- Structure-activity relationships for a novel series of thiazolyl phenyl ether derivatives exhibiting potent and selective acetyl-CoA carboxylase 2 inhibitory activity.
- PPARalpha and PPARgamma dual agonists for the treatment of type 2 diabetes and the metabolic syndrome.
- Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711).
- Effect of metformin plus roziglitazone compared with metformin alone on glycaemic control in well-controlled Type 2 diabetes.
- Endogenous insulin signaling protects cultured neurons from oxygen-glucose deprivation-induced cell death.
- Synthesis and antihyperlipidemic activity of novel glycosyl fructose derivatives.
- Combined effect of probucol and insulin on renal damage in diabetic rats fed a high cholesterol diet.
- Pyridine-2-propanoic acids: Discovery of dual PPARalpha/gamma agonists as antidiabetic agents.
- Physiologic roles of 11beta-hydroxysteroid dehydrogenase type 2 in kidney.
- The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment.
- Lack of osteopontin improves cardiac function in streptozotocin-induced diabetic mice.
- Effect of ramipril on the incidence of diabetes.
- Angiotensin-converting-enzyme inhibitors for impaired glucose tolerance--is there still hope?
- 7-But-2-ynyl-9-(6-methoxy-pyridin-3-yl)-6-piperazin-1-yl-7,9-dihydro-purin-8-one is a novel competitive and selective inhibitor of dipeptidyl peptidase IV with an antihyperglycemic activity.
- Long-term safety of pioglitazone versus glyburide in patients with recently diagnosed type 2 diabetes mellitus.
- Carvedilol versus cardioselective beta-blockers for the treatment of hypertension in patients with type 2 diabetes mellitus.
- Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome.
- Metabolic syndrome and risk of cardiovascular disease: a meta-analysis.
- Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis.
- Systemic tumor necrosis factor-related apoptosis-inducing ligand delivery shows antiatherosclerotic activity in apolipoprotein E-null diabetic mice.
- Statins and cancer risk: a literature-based meta-analysis and meta-regression analysis of 35 randomized controlled trials.
- Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type 2 diabetes mellitus.
- The chemokine (C-X-C motif) receptor 4 inhibitor AMD3100 accelerates blood flow restoration in diabetic mice.
- Structural, kinetic, and thermodynamic analysis of glucoimidazole-derived glycosidase inhibitors.
- Follicle-stimulating hormone stimulates TNF production from immune cells to enhance osteoblast and osteoclast formation.
- Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet.
- A double-blind, placebo-controlled trial assessing pramlintide treatment in the setting of intensive insulin therapy in type 1 diabetes.
- Impaired adipose tissue development in mice with inactivation of placental growth factor function.
- A selective aldose reductase inhibitor of a new structural class prevents or reverses early retinal abnormalities in experimental diabetic retinopathy.
- Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice.
- Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals.
- IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies.
- The alpha-adducin gene is associated with macrovascular complications and mortality in patients with type 2 diabetes.
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