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- Engineering of vault nanocapsules with enzymatic and fluorescent properties.
- Thalidomide in the treatment of cancer cachexia: a randomised placebo controlled trial.
- Fenofibrate reduces progression to microalbuminuria over 3 years in a placebo-controlled study in type 2 diabetes: results from the Diabetes Atherosclerosis Intervention Study (DAIS).
- Insulin protects against amyloid beta-peptide toxicity in brain mitochondria of diabetic rats.
- Is bortezomib, a proteasome inhibitor, effective in treating cancer-associated weight loss? Preliminary results from the North Central Cancer Treatment Group.
- Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase-1.
- Angiopoietin-related growth factor antagonizes obesity and insulin resistance.
- Tetrahydroisoquinoline 1-carboxamides as growth hormone secretagogues.
- Novel and potent cyclic cyanamide-based cathepsin K inhibitors.
- Structure-activity relationship studies on tetralin carboxamide growth hormone secretagogue receptor antagonists.
- Feeding responses to a melanocortin agonist and antagonist in obesity induced by a palatable high-fat diet.
- In silico ADME modelling: prediction models for blood-brain barrier permeation using a systematic variable selection method.
- Efficacy and safety of the coadministration of ezetimibe with fenofibrate in patients with mixed hyperlipidaemia.
- Hepatic glucocorticoid receptor antagonism is sufficient to reduce elevated hepatic glucose output and improve glucose control in animal models of type 2 diabetes.
- Inhibition of growth of experimental human endometrial cancer by an antagonist of growth hormone-releasing hormone.
- Target-directed proteolysis at the ribosome.
- Novel human neuropeptide Y Y5 receptor antagonists for the treatment of obesity. Synthesis and biological evaluation of pyridine hydrazide derivatives.
- Twice-daily pre-mixed insulin rather than basal insulin therapy alone results in better overall glycaemic control in patients with Type 2 diabetes.
- A long-term comparison of pioglitazone and gliclazide in patients with Type 2 diabetes mellitus: a randomized, double-blind, parallel-group comparison trial.
- Reduced cardiovascular morbidity and mortality associated with metformin use in subjects with Type 2 diabetes.
- Biphasic insulin aspart compared to biphasic human insulin reduces postprandial hyperlipidemia in patients with Type 2 diabetes.
- Effects of KR-32570, a new Na+/H+ exchanger inhibitor, on functional and metabolic impairments produced by global ischemia and reperfusion in the perfused rat heart.
- Metabolic syndrome and risk of restenosis in patients undergoing percutaneous coronary intervention.
- Effect of sibutramine on weight management and metabolic control in type 2 diabetes: a meta-analysis of clinical studies.
- Reduced hypoglycemia risk with insulin glargine: a meta-analysis comparing insulin glargine with human NPH insulin in type 2 diabetes.
- Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance.
- Adipocyte-specific glucocorticoid inactivation protects against diet-induced obesity.
- Apolipoprotein M is required for prebeta-HDL formation and cholesterol efflux to HDL and protects against atherosclerosis.
- Antipsychotic drug-induced weight gain: development of an animal model.
- In vivo imaging of oxidative stress in the kidney of diabetic mice and its normalization by angiotensin II type 1 receptor blocker.
- Identification of parathyroid hormone-regulated proteins in mouse bone marrow cells by proteomics.
- Prevalence of Vitamin D inadequacy among postmenopausal North American women receiving osteoporosis therapy.
- Parathyroid hormone-related protein (PTHrP) as a causative factor of cancer-associated wasting: possible involvement of PTHrP in the repression of locomotor activity in rats bearing human tumor xenografts.
- Discovery of a novel series of peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes and dyslipidemia.
- Discovery of bicycloalkyl urea melanin concentrating hormone receptor antagonists: orally efficacious antiobesity therapeutics.
- High-throughput lipophilicity measurement with immobilized artificial membranes.
- Role of hypothalamic 5'-AMP-activated protein kinase in the regulation of food intake and energy homeostasis.
- 2-Piperazinecarboxamides as potent and selective melanocortin subtype-4 receptor agonists.
- Discovery, synthesis and biological evaluation of novel glucokinase activators.
- Synthesis and in vivo antihyperglycemic activity of 5-(1H-pyrazol-3-yl)methyl-1H-tetrazoles.
- Change in body mass index and its impact on blood pressure: a prospective population study.
- Effects of sibutramine on abdominal fat mass, insulin resistance and blood pressure in obese hypertensive patients.
- Antiobesity effect of a melanin-concentrating hormone 1 receptor antagonist in diet-induced obese mice.
- Relief of painful diabetic peripheral neuropathy with pregabalin: a randomized, placebo-controlled trial.
- Analysis of gene expression profiles in insulin-sensitive tissues from pre-diabetic and diabetic Zucker diabetic fatty rats.
- Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action.
- Simvastatin reduced ischemic brain injury and perfusion deficits in an embolic model of stroke.
- Inhibition of appetite by nasal leptin administration in rats.
- Novel and potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors.
- Nonoxynol-9 induces apoptosis of endometrial explants by both caspase-dependent and -independent apoptotic pathways.
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