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- Protection from brain damage and bacterial infection in murine stroke by the novel caspase-inhibitor Q-VD-OPH.
- Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial.
- Once-weekly 22mug subcutaneous IFN-beta-1a in secondary progressive MS: a 3-year follow-up study on brain MRI measurements and serum MMP-9 levels.
- Neuroprotection in focal cerebral ischemia owing to delayed treatment with melanocortins.
- Rational design of 7-arylquinolines as non-competitive metabotropic glutamate receptor subtype 5 antagonists.
- Cannabidiol in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression.
- The interleukin-8 (IL-8/CXCL8) receptor inhibitor reparixin improves neurological deficits and reduces long-term inflammation in permanent and transient cerebral ischemia in rats.
- Assessment of the safety, tolerability, and PK/PD properties of two new formulations of subcutaneously administered IFN-beta1a: a double-blind, placebo-controlled comparison with the currently available formulation.
- Plasminogen activator inhibitor-1 contributes to the deleterious effect of obesity on the outcome of thrombotic ischemic stroke in mice.
- In vivo targeting of antibody fragments to the nervous system for Alzheimer's disease immunotherapy and molecular imaging of amyloid plaques.
- Re-Expression of a Developmentally Restricted Potassium Channel in Autoimmune Demyelination. Kv1.4 Is Implicated in Oligodendroglial Proliferation.
- Neuroprotective Effects of Leptin Against Ischemic Injury Induced by Oxygen-Glucose Deprivation and Transient Cerebral Ischemia.
- Effects of EP1 receptor on cerebral blood flow in the middle cerebral artery occlusion model of stroke in mice.
- A randomised double-blind placebo-controlled trial of folic acid supplementation of cholinesterase inhibitors in Alzheimer's disease.
- Phencyclidine-Induced Cognitive Deficits in Mice Are Improved by Subsequent Subchronic Administration of the Novel Selective alpha7 Nicotinic Receptor Agonist SSR180711.
- REPARIXIN, AN INHIBITOR OF CXCR2 FUNCTION, ATTENUATES INFLAMMATORY RESPONSES AND PROMOTES RECOVERY OF FUNCTION AFTER TRAUMATIC LESION TO THE SPINAL CORD.
- Synthesis and Biological Evaluation of 1-Amino-2-Phosphonomethylcyclopropanecarboxylic Acids, New Group III Metabotropic Glutamate Receptor Agonists.
- Effect of DAB(389)IL-2 immunotoxin on the course of experimental autoimmune encephalomyelitis in Lewis rats.
- A novel way of therapeutic angiogenesis using an adeno-associated virus-mediated angiogenin gene transfer.
- Neuroprotective and anticonvulsant effects of EGIS-8332, a non-competitive AMPA receptor antagonist, in a range of animal models.
- Function, structure and therapeutic potential of complement C5a receptors.
- Post-ischemic treatment with erythropoietin or carbamylated erythropoietin reduces infarction and improves neurological outcome in a rat model of focal cerebral ischemia.
- Oxcarbazepine for treating paroxysmal painful symptoms in multiple sclerosis: a pilot study.
- Attenuation of beta-amyloid-induced toxicity by sialic-acid-conjugated dendrimers: Role of sialic acid attachment.
- The synthetic cannabinoid HU-210 attenuates neural damage in diabetic mice and hyperglycemic pheochromocytoma PC12 cells.
- A phase 1, placebo-controlled, randomised, double-blind (within dose panels) study evaluating the safety, tolerability and pharmacokinetics of intravenous NXY-059 in Japanese subjects.
- N-(5-Chloro-2-(hydroxymethyl)-N-alkyl-arylsulfonamides as gamma-secretase inhibitors.
- Adeno-associated virus-mediated antiangiogenic gene therapy with thrombospondin-1 type 1 repeats and endostatin.
- Treatment guidelines for Alzheimer's disease: redefining perceptions in primary care.
- Effect of combination of endothelin receptor antagonist (TAK-044) and aspirin in middle cerebral artery occlusion model of acute ischemic stroke in rats.
- COG1410, a Novel Apolipoprotein E-Based Peptide, Improves Functional Recovery in a Murine Model of Traumatic Brain Injury.
- The Novel Apolipoprotein E-Based Peptide COG1410 Improves Sensorimotor Performance and Reduces Injury Magnitude following Cortical Contusion Injury.
- Neurological Recovery-Promoting, Anti-Inflammatory, and Anti-Oxidative Effects Afforded by Fenofibrate, a PPAR Alpha Agonist, in Traumatic Brain Injury.
- Injury-induced neurogenesis in Bax-deficient mice: evidence for regulation by voltage-gated potassium channels.
- Lovastatin improves histological and functional outcomes and reduces inflammation after experimental traumatic brain injury.
- Protective effect of erythropoietin against 1-methyl-4-phenylpyridiniuminduced neurodegenaration in PC12 cells.
- Quantitation of peripheral blood markers of rat experimental autoimmune encephalomyelitis.
- Does a change in angiotensin II formation caused by antihypertensive drugs affect the risk of stroke?: A meta-analysis of trials according to treatment with potentially different effects on angiotensin II.
- Memantine (Ebixa(R)) in Clinical Practice - Results of an Observational Study.
- Effect of Sarpogrelate, a 5-HT(2A) Antagonist, on Platelet Aggregation in Patients with Ischemic Stroke: Clinical-Pharmacological Dose-Response Study.
- Analysis of the Effect of Memantine in Reducing the Worsening of Clinical Symptoms in Patients with Moderate to Severe Alzheimer's Disease.
- Intravenous immunoglobulin in primary and secondary chronic progressive multiple sclerosis: a randomized placebo controlled multicentre study.
- Design, synthesis, and biological evaluation of tricyclic heterocycle-tetraamine conjugates as potent NMDA channel blockers.
- Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of PPAR-{alpha}
- Screening for inhibitors of tau protein aggregation into Alzheimer paired helical filaments: a ligand based approach results in successful scaffold hopping.
- DP-155, a Lecithin Derivative of Indomethacin, is a Novel Nonsteroidal Antiinflammatory Drug for Analgesia and Alzheimer's Disease Therapy.
- MCI-186 prevents brain tissue from neuronal damage in cerebral infarction through the activation of intracellular signaling.
- Brain delivery of vasoactive intestinal peptide enhanced with the nanoparticles conjugated with wheat germ agglutinin following intranasal administration.
- AC260584 (4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one), a selective muscarinic M(1) receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus.
- The selective dopamine D(3) receptor antagonists, SB 277011-A and S 33084 block haloperidol-induced catalepsy in rats.